{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:43:30Z","timestamp":1790811810464,"version":"4.1.0"},"reference-count":42,"publisher":"Canadian Science Publishing","issue":"4","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Appl. Physiol. Nutr. Metab."],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:p>Oral contraception (OC) and energy intake may play a role in fuel selection during exercise. The aim of this study was to investigate the effect of OCs (OC+ vs. OC\u2013) in fed and fasting conditions on substrate oxidation and metabolic and hormonal responses in women during exercise. Substrate oxidation (respiratory exchange ratio and lipid and carbohydrates oxidation rates), metabolic (glycerol, free fatty acids (FFA), and glucose), and hormonal (insulin, adrenaline, and noradrenaline) responses were determined in 21 women: 10 regularly menstruating women (OC\u2013) and 11 women using OCs (OC+: low-dose monophasic pill; ethinyl estradiol\u00a0\u2264 30\u00a0\u00b5g) during 45\u00a0min at 65% of maximal oxygen consumption in fasting and postprandial states. At rest, OC+ presented higher low-density lipoprotein cholesterol, total cholesterol, and triglyceride plasma concentrations as compared with OC\u2013. OC status had no influence on substrate oxidation and metabolic and hormonal responses during exercise. In the fasting state, whatever the OC status, women exhibited greater reliance on fat than in postprandial condition. This occurred in the presence of lower plasma insulin concentrations and higher plasma FFA and glycerol levels. The results indicated that the use of low-dose monophasic combined with OCs did not modify fuel selection and metabolic and hormonal responses during exercise in women. The fasting condition, compared with the fed condition, decreased carbohydrate oxidation during exercise, leading to a greater lipid mobilization and utilization whatever the OC status. Thus, in women, the realization of an exercise in either the fed or fasting conditions had a greater impact on substrate oxidation than OC status.<\/jats:p>","DOI":"10.1139\/h2012-031","type":"journal-article","created":{"date-parts":[[2012,7,5]],"date-time":"2012-07-05T14:24:30Z","timestamp":1341498270000},"page":"646-656","source":"Crossref","is-referenced-by-count":25,"title":["Oral contraception and energy intake in women: Impact on substrate oxidation during exercise"],"prefix":"10.1139","volume":"37","author":[{"given":"Laurie","family":"Isacco","sequence":"first","affiliation":[{"name":"Laboratoire des Adaptations M\u00e9taboliques \u00e0 l\u2019Exercice en conditions Physiologiques et Pathologiques (AME2P), Clermont Universit\u00e9, Universit\u00e9 Blaise Pascal, EA 3533, BP 10448, F-63000 Clermont-Ferrand, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Thivel","sequence":"additional","affiliation":[{"name":"Laboratoire des Adaptations M\u00e9taboliques \u00e0 l\u2019Exercice en conditions Physiologiques et Pathologiques (AME2P), Clermont Universit\u00e9, Universit\u00e9 Blaise Pascal, EA 3533, BP 10448, F-63000 Clermont-Ferrand, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Meddahi","family":"Pelle","sequence":"additional","affiliation":[{"name":"Bioengineering for cardiovascular imaging and therapy, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U698, 46 rue H Huchard, 75018 Paris, France."},{"name":"Intitut Universitaire de Technology (IUT) of Saint-Denis, Paris University 13, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassane","family":"Zouhal","sequence":"additional","affiliation":[{"name":"Laboratory Movement Sport and Health Sciences, University of Rennes 2, Avenue Charles Tillon, 35044 Rennes CEDEX, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"Duclos","sequence":"additional","affiliation":[{"name":"Department of Sport Medicine and Functional Explorations, Clermont-Ferrand University Hospital (CHU), G.\u00a0Montpied Hospital, Clermont-Ferrand, F-63003 France."},{"name":"Institut National de la Recherche Agronomique (INRA), UMR 1019, Clermont-Ferrand, F-63001 France."},{"name":"Unit\u00e9 de Formation et de Recherche Medicine, University Clermont 1, Clermont-Ferrand, F-63001 France."},{"name":"Centre de Recherche en Nutrition Humaine-Auvergne, Clermont-Ferrand, F-63001 France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascale","family":"Duche","sequence":"additional","affiliation":[{"name":"Laboratoire des Adaptations M\u00e9taboliques \u00e0 l\u2019Exercice en conditions Physiologiques et Pathologiques (AME2P), Clermont Universit\u00e9, Universit\u00e9 Blaise Pascal, EA 3533, BP 10448, F-63000 Clermont-Ferrand, France."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Boisseau","sequence":"additional","affiliation":[{"name":"Laboratoire des Adaptations M\u00e9taboliques \u00e0 l\u2019Exercice en conditions Physiologiques et Pathologiques (AME2P), Clermont Universit\u00e9, Universit\u00e9 Blaise Pascal, EA 3533, BP 10448, F-63000 Clermont-Ferrand, France."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"155","reference":[{"issue":"4","key":"refg1\/ref1","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1249\/00005768-199204000-00007","volume":"24","author":"Bemben D.A.","year":"1992","journal-title":"Med. 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