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Second, the awake dog and the goat at rest show an immediate and substantial depression of tidal volume and of ventilation when their isolated carotid chemoreceptors are made hypocapnic. Accordingly, it is proposed that during heavy exercise the carotid chemoreceptors are inhibitory to respiratory motor output and that the cause of the hyperventilatory response originates from extrachemoreceptor, locomotor-linked, feed-forward stimuli. Key words: hypocapnic inhibition, medullary chemoreceptors, locomotor-linked stimuli, feed-forward <\/jats:p>","DOI":"10.1139\/h94-028","type":"journal-article","created":{"date-parts":[[2008,1,22]],"date-time":"2008-01-22T16:14:38Z","timestamp":1201018478000},"page":"350-359","source":"Crossref","is-referenced-by-count":18,"title":["Do Carotid Chemoreceptors Inhibit the Hyperventilatory Response to Heavy Exercise?"],"prefix":"10.1139","volume":"19","author":[{"given":"Jerome A.","family":"Dempsey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Curtis A.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"155","reference":[{"key":"p_1\/p_1_1","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/j.1748-1716.1958.tb01601.x","volume":"43","author":"Asmussen E.","year":"1958","journal-title":"Acta Physiol. 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