{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T00:49:49Z","timestamp":1648687789998},"reference-count":0,"publisher":"Canadian Science Publishing","issue":"3","license":[{"start":{"date-parts":[[1981,3,1]],"date-time":"1981-03-01T00:00:00Z","timestamp":352252800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Microbiol."],"published-print":{"date-parts":[[1981,3,1]]},"abstract":"<jats:p> Citrobacter freundii from an environmental source displayed resistance to a wide variety of antibacterials. Some of these resistances could be transferred by conjugation with frequencies as high as 10<jats:sup>\u22122<\/jats:sup>. The complexity of plasmid involvement in the antibacterial resistance of this species was demonstrated by isolation of plasmid DNA from two isolates. In one strain, resistance to \u03b2-lactam antibiotics was specified by a 55\u2002\u00d7\u200210<jats:sup>6<\/jats:sup> molecular weight plasmid, whereas kanamycin and neomycin resistance was specified by a 7\u2002\u00d7\u200210<jats:sup>6<\/jats:sup> molecular weight plasmid. Resistance to chloramphenicol and tetracycline was not plasmid mediated. The other strain contained plasmids of molecular weight 113\u2002\u00d7\u200210<jats:sup>6<\/jats:sup> and 80\u2002\u00d7\u200210<jats:sup>6<\/jats:sup>, which specified resistance to chloramphenicol, neomycin, kanamycin, tetracycline, and mercury. <\/jats:p>","DOI":"10.1139\/m81-052","type":"journal-article","created":{"date-parts":[[2010,5,20]],"date-time":"2010-05-20T14:26:17Z","timestamp":1274365577000},"page":"343-349","source":"Crossref","is-referenced-by-count":1,"title":["Plasmid specification of resistance to antibacterial compounds in environmental <i>Citrobacter freundii<\/i>"],"prefix":"10.1139","volume":"27","author":[{"given":"R. A.","family":"Austen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. J.","family":"Trust","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"155","container-title":["Canadian Journal of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/pdf\/10.1139\/m81-052","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T00:13:31Z","timestamp":1578269611000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/10.1139\/m81-052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,3,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1981,3,1]]}},"alternative-id":["10.1139\/m81-052"],"URL":"https:\/\/doi.org\/10.1139\/m81-052","relation":{},"ISSN":["0008-4166","1480-3275"],"issn-type":[{"value":"0008-4166","type":"print"},{"value":"1480-3275","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,3,1]]}}}