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Recent publications have shown that MeCP2 is dynamically post-translationally modified, and it is possible that these marks permit MeCP2 to inhabit very diverse chromatin environments. It is also of interest to consider how nucleosome composition differs in these varying chromatin regions, and how the chromatin template itself contributes to diversifying the regulatory roles of MeCP2. These will be critical points to examine when seeking to understand how MeCP2 behaviour differentiates in tissues other than the brain. By understanding the chromatin and (or) tissue context in which MeCP2 interacts, it may be possible to discern the specific etiology of diseases linked to MeCP2 dysfunction. <\/jats:p>","DOI":"10.1139\/o09-054","type":"journal-article","created":{"date-parts":[[2009,11,2]],"date-time":"2009-11-02T13:03:42Z","timestamp":1257167022000},"page":"791-798","source":"Crossref","is-referenced-by-count":4,"title":["A moment\u2019s pause: putative nucleosome-based influences on MeCP2 regulationThis paper is one of a selection of papers published in this Special Issue, entitled 30th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal\u2019s usual peer review process."],"prefix":"10.1139","volume":"87","author":[{"given":"Anita A.","family":"Thambirajah","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC  V8W\u00a03P6, Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Ausi\u00f3","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC  V8W\u00a03P6, Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"155","reference":[{"key":"rg1\/ref1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M700855200"},{"key":"rg2\/ref2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm599"},{"key":"rg3\/ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199811000-00003"},{"key":"rg4\/ref4","doi-asserted-by":"publisher","DOI":"10.1093\/bfgp\/ell020"},{"key":"rg5\/ref5","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2275"},{"key":"rg6\/ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-002-0724-4"},{"key":"rg7\/ref7","doi-asserted-by":"publisher","DOI":"10.1139\/O07-057"},{"key":"rg8\/ref8","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200502062"},{"key":"rg9\/ref9","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki874"},{"key":"rg10\/ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-003-0497-9"},{"key":"rg11\/ref11","doi-asserted-by":"publisher","DOI":"10.1126\/science.1153252"},{"key":"rg12\/ref12","doi-asserted-by":"publisher","DOI":"10.1126\/science.1086446"},{"key":"rg13\/ref13","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddh282"},{"key":"rg14\/ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2006.04768.x"},{"key":"rg15\/ref15","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.21678"},{"key":"rg16\/ref16","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1759708"},{"key":"rg17\/ref17","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M210256200"},{"key":"rg18\/ref18","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki971"},{"key":"rg19\/ref19","doi-asserted-by":"publisher","DOI":"10.1634\/stemcells.2006-0383"},{"key":"rg20\/ref20","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M305308200"},{"key":"rg21\/ref21","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410140412"},{"key":"rg22\/ref22","doi-asserted-by":"publisher","DOI":"10.1038\/ng1516"},{"key":"rg23\/ref23","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1033.2003.03714.x"},{"issue":"11","key":"rg24\/ref24","doi-asserted-by":"crossref","first-page":"6538","DOI":"10.1128\/MCB.18.11.6538","volume":"18","author":"Hendrich B.","year":"1998","journal-title":"Mol. 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