{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T06:29:33Z","timestamp":1692340173455},"reference-count":15,"publisher":"Canadian Science Publishing","issue":"2","license":[{"start":{"date-parts":[[2004,2,1]],"date-time":"2004-02-01T00:00:00Z","timestamp":1075593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Microbiol."],"published-print":{"date-parts":[[2004,2,1]]},"abstract":"<jats:p>Of several hundred microorganisms randomly selected from the environment, only a fungal isolate identified as Aspergillus niger van Tiegham var. niger was found to transform the phytotoxin thaxtomin A to much less toxic metabolites. The rate and extent of transformation of thaxtomin A was tested under a variety of conditions, including different growth media, biomass concentrations, incubation periods, and shaker speeds. Under optimum conditions the fungus converted thaxtomin A into two major and five minor metabolites. The two major metabolites and three of the five minor metabolites were fully characterized by a combination of mass spectral and nuclear magnetic resonance techniques. When assayed on aseptically produced mini-tubers, the major metabolites proved to be much less phytotoxic than thaxtomin A.Key words: Aspergillus niger van Tiegham var. niger, biotransformation, common scab, phytotoxins, Streptomyces scabies, thaxtomin A.<\/jats:p>","DOI":"10.1139\/w03-110","type":"journal-article","created":{"date-parts":[[2004,4,2]],"date-time":"2004-04-02T16:09:02Z","timestamp":1080922142000},"page":"121-126","source":"Crossref","is-referenced-by-count":9,"title":["Biotransformation of the<i>Streptomyces scabies<\/i>phytotoxin thaxtomin A by the fungus<i>Aspergillus niger<\/i>"],"prefix":"10.1139","volume":"50","author":[{"given":"George","family":"Lazarovits","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jackie","family":"Hill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Russell R","family":"King","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larry A","family":"Calhoun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"155","reference":[{"key":"p_2\/p_2_1","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1094\/PDIS.1998.82.6.631","volume":"82","author":"Conn K.","year":"1998","journal-title":"Plant Dis."},{"key":"p_3\/p_3_1","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1094\/PHYTO.1998.88.5.442","volume":"88","author":"Goyer C.","year":"1998","journal-title":"Phytopathology"},{"key":"p_4\/p_4_1","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1046\/j.1365-2958.2000.02170.x","volume":"38","author":"Healy F.G.","year":"2000","journal-title":"Mol. 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