{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T09:38:12Z","timestamp":1648719492884},"reference-count":0,"publisher":"Canadian Science Publishing","issue":"12","license":[{"start":{"date-parts":[[1969,12,1]],"date-time":"1969-12-01T00:00:00Z","timestamp":-2678400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Physiol. Pharmacol."],"published-print":{"date-parts":[[1969,12,1]]},"abstract":"<jats:p> Expansions of extracellular space or of plasma volume were produced in rats by infusing Ringer's solution or bovine albumin 6% in Ringer's solution. Urinary volume (V), glomerular filtration rate (GFR), and the fraction of sodium escaping tubular reabsorption (TRF<jats:sub>Na+<\/jats:sub>) were measured in the two series of animals during the first 40\u2002min of infusion: an analogous increase of V and TRF<jats:sub>Na+<\/jats:sub> was observed in the two groups. On the contrary, when the infusion was continued for 100\u2002min, V, TRF<jats:sub>Na+<\/jats:sub>, and GFR of animals receiving isooncotic solution were markedly depressed. Val-5-angiotensin II-amide (0.25\u2002\u03bcg\/kg per min) was natriuretic in animals whose extracellular fluid volume had been expanded with an isotonic infusion, whereas most of the animals receiving isooncotic solutions did not respond to the octapeptide. The fraction V of bovine albumin used in the present study was devoid of a pressor effect and did not show any angiotensinase activity. The results are consistent with the hypothesis that the decrease of plasma oncotic pressure is an important factor facilitating the natriuretic effect of angiotensin. <\/jats:p>","DOI":"10.1139\/y69-158","type":"journal-article","created":{"date-parts":[[2011,4,23]],"date-time":"2011-04-23T16:39:38Z","timestamp":1303576778000},"page":"969-974","source":"Crossref","is-referenced-by-count":1,"title":["The renal action of angiotensin in rats after expansion of plasma volume or of extracellular fluid"],"prefix":"10.1139","volume":"47","author":[{"given":"D.","family":"Regoli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"155","container-title":["Canadian Journal of Physiology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/pdf\/10.1139\/y69-158","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,5]],"date-time":"2020-01-05T11:18:16Z","timestamp":1578223096000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/10.1139\/y69-158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,12,1]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1969,12,1]]}},"alternative-id":["10.1139\/y69-158"],"URL":"https:\/\/doi.org\/10.1139\/y69-158","relation":{},"ISSN":["0008-4212","1205-7541"],"issn-type":[{"value":"0008-4212","type":"print"},{"value":"1205-7541","type":"electronic"}],"subject":[],"published":{"date-parts":[[1969,12,1]]}}}