{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T10:27:59Z","timestamp":1762079279351,"version":"build-2065373602"},"reference-count":0,"publisher":"Canadian Science Publishing","issue":"3","license":[{"start":{"date-parts":[[1974,6,1]],"date-time":"1974-06-01T00:00:00Z","timestamp":139276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Physiol. Pharmacol."],"published-print":{"date-parts":[[1974,6,1]]},"abstract":"<jats:p> The effects of exhausting bicycle exercise at close to maximal work capacity upon circulating levels of hormones and energy substrates in 4 fasting growth-hormone-deficient and 15 fasting healthy subjects (aged 13\u201318 years) have been studied. As expected, only the healthy subjects showed a rise in plasma growth hormone (GH) levels. In both groups plasma insulin tended to fall, but the decline was more prolonged in the GH-de-ficient group. Plasma Cortisol levels rose in both groups with the exception of one adrenocorticotropin (ACTH)-deficient subject. Blood sugar levels were well-maintained in all but this ACTH-deficient subject, whereas both groups showed marked lactate accumulation. Both groups demonstrated an initial fall and then a secondary rise in serum free fatty acid concentrations; however, fatty acid levels were lower in the GH-deficient group and there was no post-exercise overshoot, suggesting a possible reduction in the effectiveness of lipid mobilization. <\/jats:p>","DOI":"10.1139\/y74-075","type":"journal-article","created":{"date-parts":[[2011,4,24]],"date-time":"2011-04-24T08:50:04Z","timestamp":1303635004000},"page":"575-582","source":"Crossref","is-referenced-by-count":8,"title":["The Metabolic Response to Exercise and Exhaustion in Normal and Growth-Hormone-Deficient Children"],"prefix":"10.1139","volume":"52","author":[{"given":"Jeremy S. D.","family":"Winter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"155","container-title":["Canadian Journal of Physiology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/pdf\/10.1139\/y74-075","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,5]],"date-time":"2020-01-05T16:21:23Z","timestamp":1578241283000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/10.1139\/y74-075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1974,6,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1974,6,1]]}},"alternative-id":["10.1139\/y74-075"],"URL":"https:\/\/doi.org\/10.1139\/y74-075","relation":{},"ISSN":["0008-4212","1205-7541"],"issn-type":[{"type":"print","value":"0008-4212"},{"type":"electronic","value":"1205-7541"}],"subject":[],"published":{"date-parts":[[1974,6,1]]}}}