{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T13:28:54Z","timestamp":1656077334247},"reference-count":0,"publisher":"Canadian Science Publishing","issue":"3","license":[{"start":{"date-parts":[[1980,3,1]],"date-time":"1980-03-01T00:00:00Z","timestamp":320716800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Physiol. Pharmacol."],"published-print":{"date-parts":[[1980,3,1]]},"abstract":"<jats:p> The effects of histamine on spiral strips of rabbit renal artery have been recorded. Histamine causes dose-dependent contractions of this preparation which are not antagonized by the H<jats:sub>2<\/jats:sub> receptor blocking agent metiamide, but which are blocked by the H<jats:sub>1<\/jats:sub> antagonist diphenhydramine. The p4<jats:sub>2<\/jats:sub> for the latter agent is similar to that observed at 37 \u00b0C in intestinal smooth muscle. No evidence of a relaxant population of H<jats:sub>2<\/jats:sub> receptors was encountered.Unlike that of intestinal smooth muscle, the response of strips of renal artery becomes progressively diminished at temperatures below about 20 \u00b0C, and the effect of reduced temperature on receptor subtype is thus more difficult to assess. It appears, however, that there is no change in type from the H<jats:sub>1<\/jats:sub> receptor observed at 37 \u00b0C and thus the temperature-dependent transformation which has been reported previously does not occur in all H<jats:sub>1<\/jats:sub> systems. <\/jats:p>","DOI":"10.1139\/y80-052","type":"journal-article","created":{"date-parts":[[2011,4,23]],"date-time":"2011-04-23T20:47:30Z","timestamp":1303591650000},"page":"306-309","source":"Crossref","is-referenced-by-count":2,"title":["Responses of rabbit renal artery to histamine: receptor type and temperature dependence"],"prefix":"10.1139","volume":"58","author":[{"given":"D. A.","family":"Cook","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. M.","family":"Iwanow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"155","container-title":["Canadian Journal of Physiology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/pdf\/10.1139\/y80-052","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,5]],"date-time":"2020-01-05T16:18:43Z","timestamp":1578241123000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/10.1139\/y80-052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,3,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1980,3,1]]}},"alternative-id":["10.1139\/y80-052"],"URL":"https:\/\/doi.org\/10.1139\/y80-052","relation":{},"ISSN":["0008-4212","1205-7541"],"issn-type":[{"value":"0008-4212","type":"print"},{"value":"1205-7541","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,3,1]]}}}