{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T22:53:00Z","timestamp":1757544780900},"reference-count":0,"publisher":"Canadian Science Publishing","issue":"1","license":[{"start":{"date-parts":[[1981,1,1]],"date-time":"1981-01-01T00:00:00Z","timestamp":347155200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Physiol. Pharmacol."],"published-print":{"date-parts":[[1981,1,1]]},"abstract":"<jats:p> Ethanol was administered to rats by oral intubation 3\u2002h after intraperitoneal administration of calcium carbimide. Increased blood acetaldehyde concentration and the presence of acetaldehyde in brain were found for the calcium carbimide \u2013 ethanol interaction. There was no detectable brain acetaldehyde for ethanol administration following saline treatment. The magnitude of the acetaldehyde concentration in blood and brain during the calcium carbimide \u2013 ethanol interaction was directly dependent on the doses of calcium carbimide (0.7, 3.5, 7.0\u2002mg\/kg) and ethanol (0.5, 1.0, 1.5\u2002g\/kg). There was an exponential relationship between brain acetaldehyde concentration and blood acetaldehyde concentration. The threshold blood acetaldehyde concentration, above which acetaldehyde was found in brain, was approximately 6\u2002\u03bcg\/mL. <\/jats:p>","DOI":"10.1139\/y81-011","type":"journal-article","created":{"date-parts":[[2010,11,25]],"date-time":"2010-11-25T14:47:48Z","timestamp":1290696468000},"page":"65-70","source":"Crossref","is-referenced-by-count":21,"title":["Acetaldehyde concentration in rat blood and brain during the calcium carbimide \u2013 ethanol interaction"],"prefix":"10.1139","volume":"59","author":[{"given":"D. J.","family":"Hoover","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. F.","family":"Brien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"155","container-title":["Canadian Journal of Physiology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/pdf\/10.1139\/y81-011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,5]],"date-time":"2020-01-05T16:19:12Z","timestamp":1578241152000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/10.1139\/y81-011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1981,1,1]]}},"alternative-id":["10.1139\/y81-011"],"URL":"https:\/\/doi.org\/10.1139\/y81-011","relation":{},"ISSN":["0008-4212","1205-7541"],"issn-type":[{"value":"0008-4212","type":"print"},{"value":"1205-7541","type":"electronic"}],"subject":[],"published":{"date-parts":[[1981,1,1]]}}}