{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T14:11:54Z","timestamp":1648822314971},"reference-count":0,"publisher":"Canadian Science Publishing","issue":"4","license":[{"start":{"date-parts":[[1984,4,1]],"date-time":"1984-04-01T00:00:00Z","timestamp":449625600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Physiol. Pharmacol."],"published-print":{"date-parts":[[1984,4,1]]},"abstract":"<jats:p> Weekly subcutaneous implantation of 25-mg nitrendipine pellets prevented onset of both spontaneous and deoxycorticosterone\u2013salt hypertension in rats. Discontinuance of implantation led to reappearance of hypertension after about 2 weeks in the former and led to rising though still normotensive pressures after about 3 weeks in the latter. A new implant caused blood pressures in both to drop within a day or two to normotensive levels in the case of spontaneously hypertensive rats. Nitrendipine prevented cardiac hypertrophy in steroid hypertensive rats, but not in spontaneous hypertensives. A nitrendipine pellet given 1 day before or a 30\u2002mg\/kg injection given 1\u2002h prior to the administration of a water, Na<jats:sup>+<\/jats:sup>, and K<jats:sup>+<\/jats:sup> load, prevented the diabetes insipidus-like syndrome resulting from deoxycorticosterone\u2013salt treatment, and lowered sodium but not potassium excretion. Nitrendipine did not affect steroid-induced hypernatremia and hypokalemia. <\/jats:p>","DOI":"10.1139\/y84-069","type":"journal-article","created":{"date-parts":[[2011,4,23]],"date-time":"2011-04-23T20:51:39Z","timestamp":1303591899000},"page":"436-440","source":"Crossref","is-referenced-by-count":1,"title":["Control of spontaneous and deoxycorticosterone\u2013salt hypertension and polyuria by nitrendipine pellets"],"prefix":"10.1139","volume":"62","author":[{"given":"Charles E.","family":"Hall","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shirley","family":"Hungerford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"155","container-title":["Canadian Journal of Physiology and Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/pdf\/10.1139\/y84-069","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,5]],"date-time":"2020-01-05T16:22:45Z","timestamp":1578241365000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/10.1139\/y84-069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1984,4,1]]}},"alternative-id":["10.1139\/y84-069"],"URL":"https:\/\/doi.org\/10.1139\/y84-069","relation":{},"ISSN":["0008-4212","1205-7541"],"issn-type":[{"value":"0008-4212","type":"print"},{"value":"1205-7541","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,4,1]]}}}