{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T12:39:06Z","timestamp":1700743146202},"reference-count":0,"publisher":"Canadian Science Publishing","issue":"2","license":[{"start":{"date-parts":[[1978,2,1]],"date-time":"1978-02-01T00:00:00Z","timestamp":255139200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Microbiol."],"published-print":{"date-parts":[[1978,2,1]]},"abstract":"<jats:p> Levels of several intermediary metabolites were measured in cells grown in acetate medium in order to test the hypothesis that the glyoxylate cycle is repressed by phosphoenolpyruvate (PEP). Wild-type cells had less PEP than either isocitrate dehydrogenase \u2013 deficient cells (which had greater isocitrate lyase activity than the wild type) or isocitrate dehydrogenase \u2013 deficient, citrate synthase \u2013 deficient cells (which are poorly inducible). Thus induction of the glyoxylate cycle is more complicated than a simple function of PEP concentration. No correlation between enzyme activity and the level of oxaloacetate, pyruvate, or citrate was found either. Citrate was synthesized in citrate synthase \u2013 deficient mutants, possibly via citrate lyase. <\/jats:p>","DOI":"10.1139\/m78-027","type":"journal-article","created":{"date-parts":[[2010,4,30]],"date-time":"2010-04-30T15:17:04Z","timestamp":1272640624000},"page":"149-153","source":"Crossref","is-referenced-by-count":10,"title":["Acetate metabolism in <i>Escherichia coli<\/i>"],"prefix":"10.1139","volume":"24","author":[{"given":"T. M.","family":"Lakshmi","sequence":"first","affiliation":[]},{"given":"Robert B.","family":"Helling","sequence":"additional","affiliation":[]}],"member":"155","container-title":["Canadian Journal of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/pdf\/10.1139\/m78-027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T00:07:09Z","timestamp":1578269229000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/10.1139\/m78-027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,2,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1978,2,1]]}},"alternative-id":["10.1139\/m78-027"],"URL":"https:\/\/doi.org\/10.1139\/m78-027","relation":{},"ISSN":["0008-4166","1480-3275"],"issn-type":[{"value":"0008-4166","type":"print"},{"value":"1480-3275","type":"electronic"}],"subject":[],"published":{"date-parts":[[1978,2,1]]}}}