{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T17:31:46Z","timestamp":1694885506032},"reference-count":0,"publisher":"Canadian Science Publishing","issue":"1","license":[{"start":{"date-parts":[[1970,1,1]],"date-time":"1970-01-01T00:00:00Z","timestamp":0},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Biochem."],"published-print":{"date-parts":[[1970,1,1]]},"abstract":"<jats:p> The hepatic polysomes isolated from magnesium-deficient guinea pigs did not contain the 131\u2002S ribosomal unit found in the polysomes of control animals that consumed an adequate magnesium diet ad libitum. A 64\u2002S particle not present in the controls appeared in the deficient polysomes. Restriction of the adequate diet to the quantity consumed by the deficient animals (pair-fed) had no effect on the polysome pattern, but restriction so as to maintain the same body weight (pair-weighted) caused dissociation similar to that of magnesium deficiency. Alkaline ribonuclease activity determined on total homogenates and expressed on the basis of nitrogen concentration was significantly higher in the livers of the magnesium-deficient and pair-weighted animals than in animals pair-fed or ad libitum fed the control diet. Acid ribonuclease activity in the magnesium-deficient animals was also significantly higher than in the pair-fed and ad libitum fed controls. Dietary treatment had no significant effect on the concentration of ribonuclease inhibitor in the liver. It was concluded that the effect of dietary magnesium deficiency in decreasing polysome stability is indirect and may be induced as well by severely reduced food intake. However, restricting food intake to the level consumed by magnesium-deficient animals did not decrease polysome size. It is postulated that this difference is due to an effect of low extracellular magnesium on nutrient transport. <\/jats:p>","DOI":"10.1139\/o70-004","type":"journal-article","created":{"date-parts":[[2009,12,17]],"date-time":"2009-12-17T17:11:46Z","timestamp":1261069906000},"page":"21-26","source":"Crossref","is-referenced-by-count":3,"title":["Relation of polysome structure to ribonuclease and ribonuclease inhibitor activities in livers of magnesium-deficient guinea pigs"],"prefix":"10.1139","volume":"48","author":[{"given":"Neville D.","family":"Grace","sequence":"first","affiliation":[]},{"given":"Boyd L.","family":"O'Dell","sequence":"additional","affiliation":[]}],"member":"155","container-title":["Canadian Journal of Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/pdf\/10.1139\/o70-004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,5]],"date-time":"2020-01-05T19:07:37Z","timestamp":1578251257000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/10.1139\/o70-004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1970,1,1]]}},"alternative-id":["10.1139\/o70-004"],"URL":"https:\/\/doi.org\/10.1139\/o70-004","relation":{},"ISSN":["0008-4018"],"issn-type":[{"value":"0008-4018","type":"print"}],"subject":[],"published":{"date-parts":[[1970,1,1]]}}}