{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T04:09:47Z","timestamp":1751515787809,"version":"3.41.0"},"reference-count":74,"publisher":"Canadian Science Publishing","issue":"3","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":["cdnsciencepub.com"],"crossmark-restriction":false},"short-container-title":["Appl. Physiol. Nutr. Metab."],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:p> This study compared the effects of a bout of maximal running exercise on arterial stiffness in children and adults. Right carotid blood pressure and artery stiffness indices measured by pulse wave velocity (PWV), compliance and distensibility coefficients, stiffness index \u03b1 and \u03b2 (echo-tracking), contralateral carotid blood pressure, and upper and lower limb and central\/aortic PWV (applanation tonometry) were taken at rest and 10 min after a bout of maximal treadmill running in 34 children (7.38 \u00b1 0.38 years) and 45 young adults (25.22 \u00b1 0.91 years) having similar aerobic potential. Two-by-two repeated measures analysis of variance and analysis of covariance were used to detect differences with exercise between groups. Carotid pulse pressure (PP; \u03b7<jats:sup>2<\/jats:sup> = 0.394) increased more in adults after exercise (p &lt; 0.05). Compliance (\u03b7<jats:sup>2<\/jats:sup> = 0.385) decreased in particular in adults and in those with high changes in distending pressure, similarly to stiffness index \u03b1 and \u03b2. Carotid PWV increased more in adults and was related to local changes in PP but not mean arterial pressure (MAP). Stiffness in the lower limbs decreased (\u03b7<jats:sup>2<\/jats:sup> = 0.115) but apparently only in those with small MAP changes (\u03b7<jats:sup>2<\/jats:sup> = 0.111). No significant exercise or group interaction effects were found when variables were adjusted to height. An acute bout of maximal exercise can alter arterial stiffness and hemodynamics in the carotid artery and within the active muscle beds. Arterial stiffness and hemodynamic response to metabolic demands during exercise in children simply reflect their smaller body size and may not indicate a particular physiological difference compared with adults. <\/jats:p>","DOI":"10.1139\/apnm-2015-0204","type":"journal-article","created":{"date-parts":[[2015,11,12]],"date-time":"2015-11-12T12:55:26Z","timestamp":1447332926000},"page":"266-276","update-policy":"https:\/\/doi.org\/10.1139\/csp-crossmark-policy","source":"Crossref","is-referenced-by-count":15,"title":["The acute effect of maximal exercise on central and peripheral arterial stiffness indices and hemodynamics in children and adults"],"prefix":"10.1139","volume":"41","author":[{"given":"Xavier","family":"Melo","sequence":"first","affiliation":[{"name":"Faculty of Human Kinetics, University of Lisbon, CIPER - Exercise and Health Laboratory, Estrada da Costa, Cruz Quebrada, 1495-688 Lisbon, Portugal."}]},{"given":"Bo","family":"Fernhall","sequence":"additional","affiliation":[{"name":"College of Applied Health Sciences, University of Illinois at Chicago, 808 South Wood Street, CMET 169, MC 518, Chicago, IL 60612, USA."}]},{"given":"Diana A.","family":"Santos","sequence":"additional","affiliation":[{"name":"Faculty of Human Kinetics, University of Lisbon, CIPER - Exercise and Health Laboratory, Estrada da Costa, Cruz Quebrada, 1495-688 Lisbon, Portugal."}]},{"given":"Rita","family":"Pinto","sequence":"additional","affiliation":[{"name":"Faculty of Human Kinetics, University of Lisbon, CIPER - Exercise and Health Laboratory, Estrada da Costa, Cruz Quebrada, 1495-688 Lisbon, Portugal."}]},{"given":"Nuno M.","family":"Pimenta","sequence":"additional","affiliation":[{"name":"Faculty of Human Kinetics, University of Lisbon, CIPER - Exercise and Health Laboratory, Estrada da Costa, Cruz Quebrada, 1495-688 Lisbon, Portugal."},{"name":"Sport Sciences School of Rio Maior - Polytechnic Institute of Santarem, Health and Fitness, Av. Dr. M\u00e1rio Soares, 2040-413 Rio Maior, Portugal."}]},{"given":"Lu\u00eds B.","family":"Sardinha","sequence":"additional","affiliation":[{"name":"Faculty of Human Kinetics, University of Lisbon, CIPER - Exercise and Health Laboratory, Estrada da Costa, Cruz Quebrada, 1495-688 Lisbon, Portugal."}]},{"given":"Helena","family":"Santa-Clara","sequence":"additional","affiliation":[{"name":"Faculty of Human Kinetics, University of Lisbon, CIPER - Exercise and Health Laboratory, Estrada da Costa, Cruz Quebrada, 1495-688 Lisbon, Portugal."}]}],"member":"155","reference":[{"key":"refg1\/ref1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-030722"},{"key":"refg2\/ref2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.71.2.202"},{"key":"refg3\/ref3","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.99.18.2434"},{"key":"refg4\/ref4","doi-asserted-by":"publisher","DOI":"10.3109\/03091908409032067"},{"key":"refg5\/ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2008.02.005"},{"key":"refg7\/ref7","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00002.2005"},{"issue":"5","key":"refg8\/ref8","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1001\/jama.1984.03340290044018","volume":"251","author":"Dimsdale J.E.","year":"1984","journal-title":"JAMA"},{"key":"refg9\/ref9","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00151.2014"},{"key":"refg10\/ref10","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.113.01297"},{"key":"refg11\/ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2014.11.005"},{"key":"refg12\/ref12","doi-asserted-by":"publisher","DOI":"10.1080\/08037050510008814"},{"key":"refg13\/ref13","doi-asserted-by":"publisher","DOI":"10.1097\/00126097-200010000-00002"},{"issue":"4","key":"refg14\/ref14","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1016\/0002-8703(91)90941-A","volume":"122","author":"Girerd X.","year":"1991","journal-title":"Am. Heart J."},{"key":"refg15\/ref15","doi-asserted-by":"publisher","DOI":"10.1097\/00003677-200104000-00005"},{"key":"refg16\/ref16","doi-asserted-by":"publisher","DOI":"10.1042\/CS20070080"},{"key":"refg17\/ref17","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.2005.032011"},{"key":"refg18\/ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-006-0259-9"},{"key":"refg19\/ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjhyper.2007.03.015"},{"key":"refg20\/ref20","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0b013e318031b03c"},{"key":"refg21\/ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-007-0550-4"},{"key":"refg22\/ref22","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-924290"},{"key":"refg23\/ref23","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00902.2008"},{"key":"refg24\/ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2009.03.043"},{"key":"refg25\/ref25","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu293"},{"key":"refg26\/ref26","doi-asserted-by":"publisher","DOI":"10.1139\/h10-105"},{"key":"refg27\/ref27","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1681.2000.03232.x"},{"issue":"5","key":"refg28\/ref28","first-page":"H2186","volume":"273","author":"Kingwell B.A.","year":"1997","journal-title":"Am. J. Physiol."},{"key":"refg29\/ref29","unstructured":"Klabunde, R.E. 2011. Cardiovascular physiology concepts. Lippincott Williams & Wilkins, Philadelphia, Pa, USA."},{"key":"refg30\/ref30","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000145157.07881.A3"},{"key":"refg31\/ref31","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1681.1999.03039.x"},{"key":"refg32\/ref32","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-199912000-00028"},{"key":"refg33\/ref33","doi-asserted-by":"publisher","DOI":"10.1080\/02640414.2014.889846"},{"key":"refg34\/ref34","doi-asserted-by":"publisher","DOI":"10.1080\/02640414.2013.828850"},{"key":"refg35\/ref35","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-007-0422-y"},{"issue":"7","key":"refg36\/ref36","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1038\/sj.bjp.0706805","volume":"148","author":"McEniery C.M.","year":"2006","journal-title":"Br. J. Pharmacol."},{"key":"refg37\/ref37","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-200204000-00020"},{"key":"refg38\/ref38","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00529.2002"},{"key":"refg39\/ref39","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-200203000-00012"},{"issue":"6","key":"refg40\/ref40","first-page":"575","volume":"32","author":"Novo G.","year":"2013","journal-title":"Int. Angiol."},{"key":"refg41\/ref41","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1995.tb09871.x"},{"issue":"5","key":"refg42\/ref42","first-page":"559","volume":"42","author":"Olivetti G.","year":"1980","journal-title":"Lab. Invest."},{"key":"refg43\/ref43","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000153793.84859.b8"},{"key":"refg44\/ref44","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000168052.00426.65"},{"key":"refg45\/ref45","doi-asserted-by":"publisher","DOI":"10.1152\/physiol.00052.2010"},{"key":"refg46\/ref46","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000202052.25238.68"},{"key":"refg47\/ref47","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-7061(02)02962-X"},{"key":"refg48\/ref48","doi-asserted-by":"publisher","DOI":"10.1139\/h2012-042"},{"issue":"2","key":"refg49\/ref49","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1113\/jphysiol.1994.sp020256","volume":"478","author":"Piepoli M.","year":"1994","journal-title":"J. Physiol."},{"key":"refg50\/ref50","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-008-0964-7"},{"key":"refg51\/ref51","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-011-2238-z"},{"key":"refg52\/ref52","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.109.130898"},{"key":"refg53\/ref53","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-010-1552-1"},{"issue":"2","key":"refg54\/ref54","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1152\/jappl.1990.69.2.407","volume":"69","author":"Rowell L.B.","year":"1990","journal-title":"J. Appl. Physiol."},{"key":"refg55\/ref55","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-199709000-00005"},{"key":"refg56\/ref56","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-002-1025-6"},{"issue":"2","key":"refg57\/ref57","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1113\/jphysiol.2003.040147","volume":"550","author":"Studinger P.","year":"2003","journal-title":"J. Physiol."},{"key":"refg58\/ref58","doi-asserted-by":"publisher","DOI":"10.2170\/jjphysiol.53.239"},{"key":"refg59\/ref59","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00077.2004"},{"key":"refg60\/ref60","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1390493"},{"key":"refg61\/ref61","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-012-2398-5"},{"key":"refg6\/ref6","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq165"},{"key":"refg62\/ref62","doi-asserted-by":"publisher","DOI":"10.1152\/advan.00114.2010"},{"key":"refg63\/ref63","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-009-1285-1"},{"key":"refg64\/ref64","doi-asserted-by":"publisher","DOI":"10.1097\/MBP.0000000000000052"},{"key":"refg65\/ref65","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e3283313a8a"},{"key":"refg66\/ref66","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-29076"},{"key":"refg67\/ref67","doi-asserted-by":"publisher","DOI":"10.1038\/ajh.2010.99"},{"key":"refg68\/ref68","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-014-2869-y"},{"key":"refg69\/ref69","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.109.139964"},{"key":"refg70\/ref70","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e32832cb04e"},{"key":"refg71\/ref71","doi-asserted-by":"publisher","DOI":"10.1042\/cs0920487"},{"key":"refg72\/ref72","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-5629(99)00020-4"},{"key":"refg73\/ref73","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.86.11.8013"},{"key":"refg74\/ref74","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00710.2013"}],"container-title":["Applied Physiology, Nutrition, and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/cdnsciencepub.com\/doi\/full-xml\/10.1139\/apnm-2015-0204","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/cdnsciencepub.com\/doi\/pdf\/10.1139\/apnm-2015-0204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T15:17:31Z","timestamp":1751469451000},"score":1,"resource":{"primary":{"URL":"https:\/\/cdnsciencepub.com\/doi\/10.1139\/apnm-2015-0204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":74,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1139\/apnm-2015-0204"],"URL":"https:\/\/doi.org\/10.1139\/apnm-2015-0204","relation":{},"ISSN":["1715-5312","1715-5320"],"issn-type":[{"type":"print","value":"1715-5312"},{"type":"electronic","value":"1715-5320"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"2015-04-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-11-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-11-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}