{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:17:22Z","timestamp":1760217442369},"reference-count":18,"publisher":"Canadian Science Publishing","issue":"8","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Zool."],"published-print":{"date-parts":[[2010,8]]},"abstract":"<jats:p>The subterranean blind mole rats of the superspecies Spalax ehrenbergi (Nehring, 1898) have developed several strategies to cope with changing concentrations of underground oxygen. Such an atmosphere induces the generation of reactive oxygen species that can cause oxidative damage without proper control. To understand how S.\u00a0ehrenbergi appear to be able to counteract the free radicals and avoid oxidative damage, we studied the oxidative status of the Harderian gland (an organ particularly vulnerable to oxidative stress in many rodents) in two species of the superspecies S.\u00a0ehrenbergi ( Spalax galili and Spalax judaei ) under different oxygen concentration levels, paying special attention to the antioxidant defences developed by these animals and the resulting macromolecular damage. The results presented herein reinforce the idea that S.\u00a0ehrenbergi deal better with hypoxic conditions than other rodents by regulating the activity of its antioxidant enzymes. Moreover, S.\u00a0galili is better adapted to hypoxic conditions, whereas S.\u00a0judaei appears to be better adapted to hyperoxic conditions.<\/jats:p>","DOI":"10.1139\/z10-049","type":"journal-article","created":{"date-parts":[[2010,8,19]],"date-time":"2010-08-19T20:47:41Z","timestamp":1282250861000},"page":"803-807","source":"Crossref","is-referenced-by-count":7,"title":["Antioxidant responses to variations of oxygen by the Harderian gland of different species of the superspecies Spalax ehrenbergi"],"prefix":"10.1139","volume":"88","author":[{"given":"C.","family":"Soria-Valles","sequence":"first","affiliation":[{"name":"Department of Morphology and Cellular Biology, Faculty of Medicine, University of Oviedo, Oviedo\u00a0(33006), Asturias, Spain."},{"name":"Servicio Regional de Investigaci\u00f3n y Desarrollo Agroalimentario (SERIDA), Villaviciosa, Spain."},{"name":"Laboratory of Animal Molecular Evolution, Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel."}]},{"given":"B.","family":"Caballero","sequence":"additional","affiliation":[{"name":"Department of Morphology and Cellular Biology, Faculty of Medicine, University of Oviedo, Oviedo\u00a0(33006), Asturias, Spain."},{"name":"Servicio Regional de Investigaci\u00f3n y Desarrollo Agroalimentario (SERIDA), Villaviciosa, Spain."},{"name":"Laboratory of Animal Molecular Evolution, Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel."}]},{"given":"I.","family":"Vega-Naredo","sequence":"additional","affiliation":[{"name":"Department of Morphology and Cellular Biology, Faculty of Medicine, University of Oviedo, Oviedo\u00a0(33006), Asturias, Spain."},{"name":"Servicio Regional de Investigaci\u00f3n y Desarrollo Agroalimentario (SERIDA), Villaviciosa, Spain."},{"name":"Laboratory of Animal Molecular Evolution, Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel."}]},{"given":"V.","family":"Sierra","sequence":"additional","affiliation":[{"name":"Department of Morphology and Cellular Biology, Faculty of Medicine, University of Oviedo, Oviedo\u00a0(33006), Asturias, Spain."},{"name":"Servicio Regional de Investigaci\u00f3n y Desarrollo Agroalimentario (SERIDA), Villaviciosa, Spain."},{"name":"Laboratory of Animal Molecular Evolution, Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel."}]},{"given":"C.","family":"Huidobro-Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Morphology and Cellular Biology, Faculty of Medicine, University of Oviedo, Oviedo\u00a0(33006), Asturias, Spain."},{"name":"Servicio Regional de Investigaci\u00f3n y Desarrollo Agroalimentario (SERIDA), Villaviciosa, Spain."},{"name":"Laboratory of Animal Molecular Evolution, Institute of Evolution, University of Haifa, Mount Carmel, Haifa, Israel."}]},{"given":"D. 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