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For this purpose, we exploit the framework of P systems to represent the partition of the bacterial volume into separate but communicating virtual volumes, and make use of communication rules to mimic the diffusive events. We simulate this system by means of the multivolume stochastic simulation algorithm \u03c4-DPP, and present the effects of different diffusion coefficients and of a varying number of virtual volumes over the response of the chemotactic pathway. <\/jats:p>","DOI":"10.1142\/s012905411100785x","type":"journal-article","created":{"date-parts":[[2011,1,21]],"date-time":"2011-01-21T05:43:19Z","timestamp":1295588599000},"page":"89-96","source":"Crossref","is-referenced-by-count":4,"title":["MODELING DIFFUSION IN A SIGNAL TRANSDUCTION PATHWAY: THE USE OF VIRTUAL VOLUMES IN <font>P<\/font> SYSTEMS"],"prefix":"10.1142","volume":"22","author":[{"given":"DANIELA","family":"BESOZZI","sequence":"first","affiliation":[{"name":"Universit\u00e0 degli Studi di Milano, Dipartimento di Informatica e Comunicazione, Via Comelico 39, 20135 Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"PAOLO","family":"CAZZANIGA","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi di Milano-Bicocca, Dipartimento di Informatica, Sistemistica e Comunicazione, Viale Sarca 336, 20126 Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"STEFANIA","family":"COCOLO","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi di Milano, Dipartimento di Informatica e Comunicazione, Via Comelico 39, 20135 Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GIANCARLO","family":"MAURI","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi di Milano-Bicocca, Dipartimento di Informatica, Sistemistica e Comunicazione, Viale Sarca 336, 20126 Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DARIO","family":"PESCINI","sequence":"additional","affiliation":[{"name":"Universit\u00e0 degli Studi di Milano-Bicocca, Dipartimento di Informatica, Sistemistica e Comunicazione, Viale Sarca 336, 20126 Milano, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2011,11,20]]},"reference":[{"key":"rf1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.54.6139"},{"key":"rf2","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.71.041103"},{"key":"rf3","doi-asserted-by":"publisher","DOI":"10.4204\/EPTCS.6.4"},{"key":"rf5","doi-asserted-by":"publisher","DOI":"10.1007\/3-540-29937-8"},{"key":"rf6","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9991(76)90041-3"},{"key":"rf7","doi-asserted-by":"publisher","DOI":"10.1016\/S0969-2126(98)00082-3"},{"key":"rf8","first-page":"0301","volume":"2","author":"Lipkow K.","journal-title":"PLoS Comput. 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