{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T20:33:27Z","timestamp":1764102807732},"reference-count":68,"publisher":"World Scientific Pub Co Pte Lt","issue":"05","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int. J. Neur. Syst."],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:p> The majority of operations carried out by the brain require learning complex signal patterns for future recognition, retrieval and reuse. Although learning is thought to depend on multiple forms of long-term synaptic plasticity, the way this latter contributes to pattern recognition is still poorly understood. Here, we have used a simple model of afferent excitatory neurons and interneurons with lateral inhibition, reproducing a network topology found in many brain areas from the cerebellum to cortical columns. When endowed with spike-timing dependent plasticity (STDP) at the excitatory input synapses and at the inhibitory interneuron\u2013interneuron synapses, the interneurons rapidly learned complex input patterns. Interestingly, induction of plasticity required that the network be entrained into theta-frequency band oscillations, setting the internal phase-reference required to drive STDP. Inhibitory plasticity effectively distributed multiple patterns among available interneurons, thus allowing the simultaneous detection of multiple overlapping patterns. The addition of plasticity in intrinsic excitability made the system more robust allowing self-adjustment and rescaling in response to a broad range of input patterns. The combination of plasticity in lateral inhibitory connections and homeostatic mechanisms in the inhibitory interneurons optimized mutual information (MI) transfer. The storage of multiple complex patterns in plastic interneuron networks could be critical for the generation of sparse representations of information in excitatory neuron populations falling under their control. <\/jats:p>","DOI":"10.1142\/s0129065716500209","type":"journal-article","created":{"date-parts":[[2016,4,15]],"date-time":"2016-04-15T08:21:13Z","timestamp":1460708473000},"page":"1650020","source":"Crossref","is-referenced-by-count":35,"title":["Oscillation-Driven Spike-Timing Dependent Plasticity Allows Multiple Overlapping Pattern Recognition in Inhibitory Interneuron Networks"],"prefix":"10.1142","volume":"26","author":[{"given":"Jes\u00fas A.","family":"Garrido","sequence":"first","affiliation":[{"name":"Department of Computer Architecture and Technology, University of Granada, Periodista Daniel Saucedo Aranda s\/n, Granada, 18071, Spain"}]},{"given":"Niceto R.","family":"Luque","sequence":"additional","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, U968 and Centre National de la Recherche Scientifique, UMR_7210, Institut de la Vision, rue Moreau, 17, Paris, F75012, France"},{"name":"Sorbonne Universit\u00e9s, Universit\u00e9 Pierre et Marie Curie Paris 06, UMR_S 968, Place Jussieu, 4, Paris, F75252, France"}]},{"given":"Silvia","family":"Tolu","sequence":"additional","affiliation":[{"name":"Center for Playware, Department of Electrical Engineering, Technical University of Denmark, Richard Petersens Plads, Elektrovej, Building 326, Lyngby, Copenhagen, 2800, Denmark"}]},{"given":"Egidio","family":"D\u2019Angelo","sequence":"additional","affiliation":[{"name":"Department of Brain and Behavioral Sciences, University of Pavia, Via Forlanini, 6, Pavia, I27100, Italy"},{"name":"Brain Connectivity Center, Istituto Neurologico IRCCS Fondazione Casimiro Mondino, Via Mondino, 2 Pavia, I27100, Italy"}]}],"member":"219","published-online":{"date-parts":[[2016,6,8]]},"reference":[{"key":"S0129065716500209BIB001","doi-asserted-by":"publisher","DOI":"10.1038\/361031a0"},{"key":"S0129065716500209BIB002","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2010.187559"},{"key":"S0129065716500209BIB003","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80726-6"},{"key":"S0129065716500209BIB004","doi-asserted-by":"publisher","DOI":"10.1007\/s00422-008-0290-5"},{"key":"S0129065716500209BIB005","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0021649"},{"key":"S0129065716500209BIB006","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/13.1.100"},{"key":"S0129065716500209BIB007","doi-asserted-by":"publisher","DOI":"10.1038\/nature12015"},{"key":"S0129065716500209BIB008","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3683"},{"key":"S0129065716500209BIB009","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.31.060407.125639"},{"key":"S0129065716500209BIB010","doi-asserted-by":"publisher","DOI":"10.1126\/science.275.5297.213"},{"key":"S0129065716500209BIB011","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.18-24-10464.1998"},{"key":"S0129065716500209BIB012","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)00008-8"},{"key":"S0129065716500209BIB013","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0001377"},{"key":"S0129065716500209BIB014","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2207-09.2009"},{"key":"S0129065716500209BIB015","doi-asserted-by":"publisher","DOI":"10.1162\/neco.2008.06-08-804"},{"key":"S0129065716500209BIB016","doi-asserted-by":"publisher","DOI":"10.1142\/S0129065705000025"},{"key":"S0129065716500209BIB017","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2015.03.014"},{"key":"S0129065716500209BIB018","doi-asserted-by":"publisher","DOI":"10.1126\/science.1211095"},{"key":"S0129065716500209BIB019","doi-asserted-by":"publisher","DOI":"10.3389\/fncom.2014.00053"},{"key":"S0129065716500209BIB020","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4188-12.2013"},{"key":"S0129065716500209BIB021","doi-asserted-by":"publisher","DOI":"10.1142\/S0129065706000524"},{"key":"S0129065716500209BIB022","doi-asserted-by":"publisher","DOI":"10.1142\/S0129065710002553"},{"key":"S0129065716500209BIB023","doi-asserted-by":"publisher","DOI":"10.3389\/fnsyn.2010.00005"},{"key":"S0129065716500209BIB024","doi-asserted-by":"publisher","DOI":"10.3389\/fncom.2011.00047"},{"key":"S0129065716500209BIB025","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4502-12.2013"},{"key":"S0129065716500209BIB026","doi-asserted-by":"publisher","DOI":"10.1126\/science.8178157"},{"key":"S0129065716500209BIB027","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphysparis.2004.01.005"},{"key":"S0129065716500209BIB028","doi-asserted-by":"publisher","DOI":"10.3389\/fncom.2015.00138"},{"key":"S0129065716500209BIB029","doi-asserted-by":"publisher","DOI":"10.1142\/S012906571350010X"},{"key":"S0129065716500209BIB030","doi-asserted-by":"publisher","DOI":"10.1142\/S0129065711002900"},{"key":"S0129065716500209BIB031","doi-asserted-by":"publisher","DOI":"10.1109\/TSMCB.2011.2138693"},{"key":"S0129065716500209BIB032","doi-asserted-by":"publisher","DOI":"10.1016\/j.neunet.2009.04.003"},{"key":"S0129065716500209BIB033","doi-asserted-by":"publisher","DOI":"10.3233\/ICA-2007-14301"},{"key":"S0129065716500209BIB034","doi-asserted-by":"publisher","DOI":"10.1142\/S0129065714400061"},{"key":"S0129065716500209BIB035","doi-asserted-by":"publisher","DOI":"10.1142\/S012906571250013X"},{"key":"S0129065716500209BIB036","doi-asserted-by":"publisher","DOI":"10.1142\/S0129065714500026"},{"key":"S0129065716500209BIB037","doi-asserted-by":"publisher","DOI":"10.1142\/S0129065714300034"},{"key":"S0129065716500209BIB038","doi-asserted-by":"publisher","DOI":"10.1142\/S0129065714400012"},{"key":"S0129065716500209BIB039","doi-asserted-by":"publisher","DOI":"10.1142\/S0129065709002002"},{"key":"S0129065716500209BIB040","doi-asserted-by":"publisher","DOI":"10.1142\/S0129065715500409"},{"key":"S0129065716500209BIB041","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511815706"},{"key":"S0129065716500209BIB042","doi-asserted-by":"publisher","DOI":"10.1109\/TAMD.2012.2211101"},{"key":"S0129065716500209BIB043","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(03)00507-5"},{"key":"S0129065716500209BIB044","doi-asserted-by":"publisher","DOI":"10.4249\/scholarpedia.1430"},{"key":"S0129065716500209BIB045","doi-asserted-by":"publisher","DOI":"10.4249\/scholarpedia.1658"},{"key":"S0129065716500209BIB046","volume-title":"Numerical Recipes: The Art of Scientific Computing","author":"Press W. H.","year":"2007","edition":"3"},{"key":"S0129065716500209BIB047","doi-asserted-by":"publisher","DOI":"10.3389\/neuro.11.012.2008"},{"key":"S0129065716500209BIB048","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1152\/jn.1998.79.3.1592","volume":"79","author":"Leung L. S.","year":"1998","journal-title":"J. Neurophysiol."},{"key":"S0129065716500209BIB049","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1523\/JNEUROSCI.21-03-00759.2001","volume":"21","author":"D\u2019Angelo E.","year":"2001","journal-title":"J. Neurosci."},{"key":"S0129065716500209BIB050","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2013.00064"},{"key":"S0129065716500209BIB051","doi-asserted-by":"publisher","DOI":"10.3389\/neuro.03.004.2007"},{"key":"S0129065716500209BIB052","doi-asserted-by":"publisher","DOI":"10.1038\/9165"},{"key":"S0129065716500209BIB053","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1248"},{"key":"S0129065716500209BIB054","doi-asserted-by":"publisher","DOI":"10.1142\/S0129065714400048"},{"key":"S0129065716500209BIB055","first-page":"153","volume":"28","author":"D\u2019Angelo E.","year":"2013","journal-title":"Funct. Neurol."},{"key":"S0129065716500209BIB056","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1000757"},{"key":"S0129065716500209BIB057","doi-asserted-by":"crossref","first-page":"8812","DOI":"10.1523\/JNEUROSCI.20-23-08812.2000","volume":"20","author":"van Rossum M. C.","year":"2000","journal-title":"J. Neurosci."},{"key":"S0129065716500209BIB058","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.10.008"},{"key":"S0129065716500209BIB059","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1327"},{"key":"S0129065716500209BIB060","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)81202-7"},{"key":"S0129065716500209BIB061","doi-asserted-by":"publisher","DOI":"10.1038\/36103"},{"key":"S0129065716500209BIB062","doi-asserted-by":"publisher","DOI":"10.3389\/fncom.2013.00064"},{"key":"S0129065716500209BIB063","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2013.00159"},{"key":"S0129065716500209BIB064","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2009.01.048"},{"key":"S0129065716500209BIB065","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2006.02.006"},{"key":"S0129065716500209BIB066","doi-asserted-by":"publisher","DOI":"10.1142\/S0129065714400024"},{"key":"S0129065716500209BIB067","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.04.045"},{"key":"S0129065716500209BIB068","doi-asserted-by":"publisher","DOI":"10.7551\/mitpress\/9780262013277.003.0007"}],"container-title":["International Journal of Neural Systems"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.worldscientific.com\/doi\/pdf\/10.1142\/S0129065716500209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,6]],"date-time":"2019-08-06T15:20:18Z","timestamp":1565104818000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.worldscientific.com\/doi\/abs\/10.1142\/S0129065716500209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,8]]},"references-count":68,"journal-issue":{"issue":"05","published-online":{"date-parts":[[2016,6,8]]},"published-print":{"date-parts":[[2016,8]]}},"alternative-id":["10.1142\/S0129065716500209"],"URL":"https:\/\/doi.org\/10.1142\/s0129065716500209","relation":{},"ISSN":["0129-0657","1793-6462"],"issn-type":[{"value":"0129-0657","type":"print"},{"value":"1793-6462","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,8]]}}}