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EEG power spectrum was calculated on the 20[Formula: see text]s preceding SPES. Results: 121 channels showed responses to 32 stimulation sites. A single system could model the response in 41.3% and two systems were required in 58.7%. Peaks in the frequency response of the models tended to occur within the frequency range of most activity on the spontaneous EEG. Discrepancies were noted between activity predicted by models and activity recorded in the spontaneous EEG. These discrepancies could be explained by the existence of alpha rhythm or interictal epileptiform discharges. Conclusions: Cortical interactions shown by SPES can be described as control systems which can predict cortical oscillatory behavior. The method is unique as it describes connectivity as well as dynamic interactions.<\/jats:p>","DOI":"10.1142\/s0129065717500575","type":"journal-article","created":{"date-parts":[[2017,11,24]],"date-time":"2017-11-24T03:01:45Z","timestamp":1511492505000},"page":"1750057","source":"Crossref","is-referenced-by-count":22,"title":["Characterizing EEG Cortical Dynamics and Connectivity with Responses to Single Pulse Electrical Stimulation (SPES)"],"prefix":"10.1142","volume":"28","author":[{"given":"Gonzalo","family":"Alarc\u00f3n","sequence":"first","affiliation":[{"name":"Comprehensive Epilepsy Center Neuroscience Institute, Academic Health Systems, Hamad Medical Corporation, Doha, Qatar"},{"name":"Department of Clinical Neuroscience, King\u2019s College London, Institute of Psychiatry, Psychology and Neuroscience London, UK"},{"name":"Department of Clinical Neurophysiology, King\u2019s College Hospital NHS FT, London, UK"},{"name":"Weill Cornell Medical College, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Jim\u00e9nez-Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience, King\u2019s College London, Institute of Psychiatry, Psychology and Neuroscience London, UK"},{"name":"Department of Clinical Neurophysiology, King\u2019s College Hospital NHS FT, London, UK"},{"name":"Universidad San Francisco de Quito, School of Medicine, Quito, Ecuador"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Valent\u00edn","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience, King\u2019s College London, Institute of Psychiatry, Psychology and Neuroscience London, UK"},{"name":"Department of Clinical Neurophysiology, King\u2019s College Hospital NHS FT, London, UK"},{"name":"Weill Cornell Medical College, Doha, Qatar"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Mart\u00edn-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience, King\u2019s College London, Institute of Psychiatry, Psychology and Neuroscience London, UK"},{"name":"Weill Cornell Medical College, Doha, Qatar"},{"name":"Department of Clinical Neurophysiology, Kingston Hospital NHS FT, London, UK"},{"name":"Department of Clinical Neurophysiology, St George\u2019s University Hospitals NHS FT, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2018,6,24]]},"reference":[{"key":"S0129065717500575BIB001","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.57.4.435"},{"key":"S0129065717500575BIB002","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/120.12.2259"},{"key":"S0129065717500575BIB003","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2010.07.003"},{"key":"S0129065717500575BIB004","doi-asserted-by":"publisher","DOI":"10.3389\/fnsys.2010.00154"},{"key":"S0129065717500575BIB005","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2014.00261"},{"key":"S0129065717500575BIB006","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2007.05730.x"},{"key":"S0129065717500575BIB007","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf187"},{"key":"S0129065717500575BIB008","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000171340.73078.c1"},{"key":"S0129065717500575BIB009","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2009.02056.x"},{"key":"S0129065717500575BIB010","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2012.12.012"},{"key":"S0129065717500575BIB011","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh246"},{"key":"S0129065717500575BIB012","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.21407"},{"key":"S0129065717500575BIB013","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1684\/epd.2010.0334","volume":"12","author":"Iwasaki M.","year":"2010","journal-title":"Epileptic Disord."},{"key":"S0129065717500575BIB014","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2012.08.026"},{"key":"S0129065717500575BIB015","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2011.06.030"},{"key":"S0129065717500575BIB016","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2013.0528"},{"key":"S0129065717500575BIB017","doi-asserted-by":"publisher","DOI":"10.1097\/WNP.0b013e31818f4fec"},{"key":"S0129065717500575BIB018","doi-asserted-by":"publisher","DOI":"10.1007\/BF00231248"},{"key":"S0129065717500575BIB019","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1977.00500210029003"},{"key":"S0129065717500575BIB020","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1152\/ajplegacy.1942.135.3.690","volume":"135","author":"Rosenblueth A.","year":"1942","journal-title":"Am. 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