{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T11:20:26Z","timestamp":1772104826662,"version":"3.50.1"},"reference-count":46,"publisher":"World Scientific Pub Co Pte Lt","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int. J. Neur. Syst."],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p> The aim of this study was to develop methods for detecting the nonstationary periodic characteristics of neonatal electroencephalographic (EEG) seizures by adapting estimates of the correlation both in the time (spike correlation; SC) and time\u2013frequency domain (time\u2013frequency correlation; TFC). These measures were incorporated into a seizure detection algorithm (SDA) based on a support vector machine to detect periods of seizure and nonseizure. The performance of these nonstationary correlation measures was evaluated using EEG recordings from 79 term neonates annotated by three human experts. The proposed measures were highly discriminative for seizure detection (median [Formula: see text]: 0.933 IQR: 0.821\u20130.975, median [Formula: see text]: 0.883 IQR: 0.707\u20130.931). The resultant SDA applied to multi-channel recordings had a median AUC of 0.988 (IQR: 0.931\u20130.998) when compared to consensus annotations, outperformed two state-of-the-art SDAs [Formula: see text] and was noninferior to the human expert for 73\/79 of neonates. <\/jats:p>","DOI":"10.1142\/s0129065718500302","type":"journal-article","created":{"date-parts":[[2018,6,24]],"date-time":"2018-06-24T23:31:19Z","timestamp":1529883079000},"page":"1850030","source":"Crossref","is-referenced-by-count":77,"title":["Time-Varying EEG Correlations Improve Automated Neonatal Seizure Detection"],"prefix":"10.1142","volume":"29","author":[{"given":"Karoliina T.","family":"Tapani","sequence":"first","affiliation":[{"name":"BABA Center, Children\u2019s Hospital, HUS Medical Imaging Center, Clinical Neurophysiology, University of Helsinki, Helsinki University Hospital and University of Helsinki, Finland"},{"name":"Medical Imaging and Radiation Therapy, Kymenlaakso Central Hospital, Kymenlaakso Social and Health Services (Carea) Kotka, Finland"}]},{"given":"Sampsa","family":"Vanhatalo","sequence":"additional","affiliation":[{"name":"BABA Center, Children\u2019s Hospital, HUS Medical Imaging Center, Clinical Neurophysiology, University of Helsinki, Helsinki University Hospital and University of Helsinki, Finland"}]},{"given":"Nathan J.","family":"Stevenson","sequence":"additional","affiliation":[{"name":"Clinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland"},{"name":"Brain Modelling Group, QIMR Berghofer Medical Research Institute, Brisbane, Australia"}]}],"member":"219","published-online":{"date-parts":[[2019,5,15]]},"reference":[{"key":"S0129065718500302BIB001","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2009.11.067"},{"key":"S0129065718500302BIB002","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.58.4.542"},{"key":"S0129065718500302BIB003","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2005.086314"},{"key":"S0129065718500302BIB004","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(92)90179-L"},{"key":"S0129065718500302BIB005","doi-asserted-by":"publisher","DOI":"10.1016\/S0013-4694(97)00003-9"},{"key":"S0129065718500302BIB006","doi-asserted-by":"publisher","DOI":"10.1109\/10.995684"},{"key":"S0129065718500302BIB007","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2006.02.016"},{"key":"S0129065718500302BIB008","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2008.07.281"},{"key":"S0129065718500302BIB009","doi-asserted-by":"publisher","DOI":"10.1097\/WNP.0b013e3181b2f29d"},{"key":"S0129065718500302BIB010","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2010.06.034"},{"key":"S0129065718500302BIB011","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2016.06.018"},{"key":"S0129065718500302BIB012","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.249"},{"key":"S0129065718500302BIB013","doi-asserted-by":"publisher","DOI":"10.1109\/51.956817"},{"key":"S0129065718500302BIB014","doi-asserted-by":"publisher","DOI":"10.1109\/51.956820"},{"key":"S0129065718500302BIB015","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2006.886667"},{"key":"S0129065718500302BIB016","doi-asserted-by":"publisher","DOI":"10.1016\/j.medengphy.2011.08.001"},{"key":"S0129065718500302BIB017","first-page":"1265","author":"Khlif M. 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