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Syst."],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p> Working memory (WM) is a crucial cognitive process and its disruption is among the earliest symptoms of Alzheimer\u2019s disease. While alterations of the neuronal processes underlying WM have been evidenced in mild cognitive impairment (MCI), scarce literature is available in subjective cognitive decline (SCD). We used magnetoencephalography during a WM task performed by MCI [Formula: see text], SCD [Formula: see text] and healthy elders [Formula: see text] to examine group differences during the maintenance period (0\u20134000[Formula: see text]ms). Data were analyzed using time\u2013frequency analysis and significant oscillatory differences were localized at the source level. Our results indicated significant differences between groups, mainly during the early maintenance (250\u20131250[Formula: see text]ms) in the theta, alpha and beta bands and in the late maintenance (2750\u20133750[Formula: see text]ms) in the theta band. MCI showed lower local synchronization in fronto-temporal cortical regions in the early theta\u2013alpha window relative to controls [Formula: see text] and SCD [Formula: see text], and in the late theta window relative to controls [Formula: see text] and SCD [Formula: see text]. Early theta\u2013alpha power was significantly correlated with memory scores [Formula: see text] and late theta power was correlated with task performance [Formula: see text] and functional activity scores [Formula: see text]. In the early beta window, MCI showed reduced power in temporo-posterior regions relative to controls [Formula: see text] and SCD [Formula: see text]. Our results may suggest that these alterations would reflect that memory-related networks are damaged. <\/jats:p>","DOI":"10.1142\/s0129065719500199","type":"journal-article","created":{"date-parts":[[2019,6,19]],"date-time":"2019-06-19T07:22:16Z","timestamp":1560928936000},"page":"1950019","source":"Crossref","is-referenced-by-count":23,"title":["Spatiotemporal Oscillatory Patterns During Working Memory Maintenance in Mild Cognitive Impairment and Subjective Cognitive Decline"],"prefix":"10.1142","volume":"30","author":[{"given":"N.","family":"Serrano","sequence":"first","affiliation":[{"name":"Department of Experimental Psychology, Complutense University of Madrid, Pozuelo de Alarc\u00f3n, Madrid 28223, Spain"},{"name":"Laboratory of Cognitive and Computational Neuroscience (UCM-UPM), Center for Biomedical Technology (CTB), Pozuelo de Alarc\u00f3n, Madrid 28223, Spain"}]},{"given":"D.","family":"L\u00f3pez-Sanz","sequence":"additional","affiliation":[{"name":"Department of Experimental Psychology, Complutense University of Madrid, Pozuelo de Alarc\u00f3n, Madrid 28223, Spain"},{"name":"Laboratory of Cognitive and Computational Neuroscience (UCM-UPM), Center for Biomedical Technology (CTB), Pozuelo de Alarc\u00f3n, Madrid 28223, Spain"}]},{"given":"R.","family":"Bru\u00f1a","sequence":"additional","affiliation":[{"name":"Department of Experimental Psychology, Complutense University of Madrid, Pozuelo de Alarc\u00f3n, Madrid 28223, Spain"},{"name":"Laboratory of Cognitive and Computational Neuroscience (UCM-UPM), Center for Biomedical Technology (CTB), Pozuelo de Alarc\u00f3n, Madrid 28223, Spain"},{"name":"CIBER\u2019s Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Institute of Health Carlos III, Madrid, Spain"}]},{"given":"P.","family":"Garc\u00e9s","sequence":"additional","affiliation":[{"name":"Laboratory of Cognitive and Computational Neuroscience (UCM-UPM), Center for Biomedical Technology (CTB), Pozuelo de Alarc\u00f3n, Madrid 28223, Spain"}]},{"given":"I. 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