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J. Neur. Syst."],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:p> Hybrid Brain\u2013Computer Interfaces (BCIs) for upper limb rehabilitation after stroke should enable the reinforcement of \u201cmore normal\u201d brain and muscular activity. Here, we propose the combination of corticomuscular coherence (CMC) and intermuscular coherence (IMC) as control features for a novel hybrid BCI for rehabilitation purposes. Multiple electroencephalographic (EEG) signals and surface electromyography (EMG) from 5 muscles per side were collected in 20 healthy participants performing finger extension (Ext) and grasping (Grasp) with both dominant and non-dominant hand. Grand average of CMC and IMC patterns showed a bilateral sensorimotor area as well as multiple muscles involvement. CMC and IMC values were used as features to classify each task versus rest and Ext versus Grasp. We demonstrated that a combination of CMC and IMC features allows for classification of both movements versus rest with better performance (Area Under the receiver operating characteristic Curve, AUC) for the Ext movement (0.97) with respect to Grasp (0.88). Classification of Ext versus Grasp also showed high performances (0.99). All in all, these preliminary findings indicate that the combination of CMC and IMC could provide for a comprehensive framework for simple hand movements to eventually be employed in a hybrid BCI system for post-stroke rehabilitation. <\/jats:p>","DOI":"10.1142\/s0129065721500520","type":"journal-article","created":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T14:35:15Z","timestamp":1633012515000},"source":"Crossref","is-referenced-by-count":27,"title":["Corticomuscular and Intermuscular Coupling in Simple Hand Movements to Enable a Hybrid Brain\u2013Computer Interface"],"prefix":"10.1142","volume":"31","author":[{"given":"Emma","family":"Colamarino","sequence":"first","affiliation":[{"name":"Department of Computer, Control and Management Engineering, Sapienza University of Rome, Via Ariosto 25, Rome 00185, Italy"},{"name":"Fondazione Santa Lucia IRCCS, Via Ardeatina 306-354, Rome 00179, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"de Seta","sequence":"additional","affiliation":[{"name":"Department of Computer, Control and Management Engineering, Sapienza University of Rome, Via Ariosto 25, Rome 00185, Italy"},{"name":"Fondazione Santa Lucia IRCCS, Via Ardeatina 306-354, Rome 00179, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcella","family":"Masciullo","sequence":"additional","affiliation":[{"name":"Fondazione Santa Lucia IRCCS, Via Ardeatina 306-354, Rome 00179, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Febo","family":"Cincotti","sequence":"additional","affiliation":[{"name":"Department of Computer, Control and Management Engineering, Sapienza University of Rome, Via Ariosto 25, Rome 00185, Italy"},{"name":"Fondazione Santa Lucia IRCCS, Via Ardeatina 306-354, Rome 00179, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donatella","family":"Mattia","sequence":"additional","affiliation":[{"name":"Fondazione Santa Lucia IRCCS, Via Ardeatina 306-354, Rome 00179, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Floriana","family":"Pichiorri","sequence":"additional","affiliation":[{"name":"Fondazione Santa Lucia IRCCS, Via Ardeatina 306-354, Rome 00179, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jlenia","family":"Toppi","sequence":"additional","affiliation":[{"name":"Department of Computer, Control and Management Engineering, Sapienza University of Rome, Via Ariosto 25, Rome 00185, Italy"},{"name":"Fondazione Santa Lucia IRCCS, Via Ardeatina 306-354, Rome 00179, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2021,9,30]]},"reference":[{"key":"S0129065721500520BIB001","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1002\/acn3.544","volume":"5","author":"Cervera M. 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