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J. Neur. Syst."],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>Deep learning for automated interictal epileptiform discharge (IED) detection has been topical with many published papers in recent years. All existing works viewed EEG signals as time-series and developed specific models for IED classification; however, general time-series classification (TSC) methods were not considered. Moreover, none of these methods were evaluated on any public datasets, making direct comparisons challenging. This paper explored two state-of-the-art convolutional-based TSC algorithms, InceptionTime and Minirocket, on IED detection. We fine-tuned and cross-evaluated them on a public (Temple University Events \u2014 TUEV) and two private datasets and provided ready metrics for benchmarking future work. We observed that the optimal parameters correlated with the clinical duration of an IED and achieved the best area under precision-recall curve (AUPRC) of 0.98 and F1 of 0.80 on the private datasets, respectively. The AUPRC and F1 on the TUEV dataset were 0.99 and 0.97, respectively. While algorithms trained on the private sets maintained their performance when tested on the TUEV data, those trained on TUEV could not generalize well to the private data. These results emerge from differences in the class distributions across datasets and indicate a need for public datasets with a better diversity of IED waveforms, background activities and artifacts to facilitate standardization and benchmarking of algorithms.<\/jats:p>","DOI":"10.1142\/s0129065723500016","type":"journal-article","created":{"date-parts":[[2022,9,25]],"date-time":"2022-09-25T10:03:20Z","timestamp":1664100200000},"source":"Crossref","is-referenced-by-count":20,"title":["Automated Interictal Epileptiform Discharge Detection from Scalp EEG Using Scalable Time-series Classification Approaches"],"prefix":"10.1142","volume":"33","author":[{"given":"D.","family":"Nhu","sequence":"first","affiliation":[{"name":"Department of Data Science and Artificial Intelligence, Faculty of Information Technology, Monash University, Melbourne, VIC, Australia"}]},{"given":"M.","family":"Janmohamed","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia"}]},{"given":"L.","family":"Shakhatreh","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia"}]},{"given":"O.","family":"Gonen","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia"}]},{"given":"P.","family":"Perucca","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia"},{"name":"Bladin-Berkovic Comprehensive Epilepsy Program, Department of Neurology, Austin Health, Melbourne, VIC, Australia"},{"name":"Epilepsy Research Center, Department of Medicine (Austin Health), The University of Melbourne, Melbourne, VIC, Australia"}]},{"given":"A.","family":"Gilligan","sequence":"additional","affiliation":[{"name":"Bladin-Berkovic Comprehensive Epilepsy Program, Department of Neurology, Austin Health, Melbourne, VIC, Australia"},{"name":"Neurosciences Clinical Institute, Epworth Healthcare, Melbourne, VIC, Australia"}]},{"given":"P.","family":"Kwan","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC, Australia"}]},{"given":"T. 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