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Due to the large number of features of gene expression datasets, the search of a highly accurate combination of features is done by means of the new Estimation of Distribution Algorithms paradigm. In order to assess the accuracy level of the proposed approach, the na\u00efve-Bayes classification algorithm is employed in a wrapper form. Promising results are achieved, in addition to a considerable reduction in the number of genes. Stating the optimal selection of genes as a search task, an automatic and robust choice in the genes finally selected is performed, in contrast to previous works that research the same types of problems.<\/jats:p>","DOI":"10.1142\/s0218001404003800","type":"journal-article","created":{"date-parts":[[2005,1,3]],"date-time":"2005-01-03T11:23:51Z","timestamp":1104751431000},"page":"1373-1390","source":"Crossref","is-referenced-by-count":56,"title":["GENE SELECTION FOR CANCER CLASSIFICATION USING WRAPPER APPROACHES"],"prefix":"10.1142","volume":"18","author":[{"given":"ROSA","family":"BLANCO","sequence":"first","affiliation":[{"name":"Computer Science and Artificial Intelligence Department, University of Basque Country, P.O.Box 649, 20080 San Sebasti\u00e1n \u2014 Donostia, Spain"}]},{"given":"PEDRO","family":"LARRA\u00d1AGA","sequence":"additional","affiliation":[{"name":"Computer Science and Artificial Intelligence Department, University of Basque Country, P.O.Box 649, 20080 San Sebasti\u00e1n \u2014 Donostia, Spain"}]},{"given":"I\u00d1AKI","family":"INZA","sequence":"additional","affiliation":[{"name":"Computer Science and Artificial Intelligence Department, University of Basque Country, P.O.Box 649, 20080 San Sebasti\u00e1n \u2014 Donostia, Spain"}]},{"given":"BASILIO","family":"SIERRA","sequence":"additional","affiliation":[{"name":"Computer Science and Artificial Intelligence Department, University of Basque Country, P.O.Box 649, 20080 San Sebasti\u00e1n \u2014 Donostia, Spain"}]}],"member":"219","published-online":{"date-parts":[[2011,11,21]]},"reference":[{"key":"rf2","unstructured":"H.\u00a0Almuallim and T. 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