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Our contribution deals with: (i) a new model for nanowire FETs used to evaluate transistor\u2019s essential performance; (ii) a new switch-level simulator for nanoarray structure used to evaluate its switching activity; (iii) a nanoarray implementation for biosequence alignment based on a systolic array and the modeling of its essential performance based on (i) and (ii); (iv) the evaluation of the potential improvement of the nanoarray-based systolic structure with respect to an equivalent CMOS one in terms of processing capabilities, area, and power dissipation. Depending on the possible technological scenario, the performance of nanoarray is impressive, especially considering the density achievable in terms of processing per unit area. A wide solution space can be explored to find the optimal solution in terms of trading power and performance considering the technological limitations of a realistic implementation. <\/jats:p>","DOI":"10.1142\/s0218126618501943","type":"journal-article","created":{"date-parts":[[2018,3,16]],"date-time":"2018-03-16T02:20:52Z","timestamp":1521166852000},"page":"1850194","source":"Crossref","is-referenced-by-count":0,"title":["Nanoarrays for Systolic Biosequence Analysis"],"prefix":"10.1142","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6298-3856","authenticated-orcid":false,"given":"Malik Ashter","family":"Mehdy","sequence":"first","affiliation":[{"name":"Department of Electronics and Telecommunication, Politecnico di Torino, Corso Duca Degli Abruzzi 24, 10129 Torino (TO), Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleandro","family":"Antidormi","sequence":"additional","affiliation":[{"name":"Department of Electronics and Telecommunication, 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