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Data from twenty-eight seizures were available and used to develop and test the procedure in terms of the agreement between the computationally identified seizure end-point compared against the ratings of an expert clinical electroencephalographer. Generalizations to multivariate seizure onset detection and to seizure prediction are described. <\/jats:p>","DOI":"10.1142\/s0218127403008132","type":"journal-article","created":{"date-parts":[[2003,10,16]],"date-time":"2003-10-16T10:47:26Z","timestamp":1066301246000},"page":"2641-2655","source":"Crossref","is-referenced-by-count":0,"title":["Quantitative Determination of Abrupt Changes in Dynamical Systems: Illustration Via Identification of Seizure Termination  in Generalized Tonic\u2013Clonic Seizure EEG Data"],"prefix":"10.1142","volume":"13","author":[{"given":"C. J.","family":"Cellucci","sequence":"first","affiliation":[{"name":"Department of Physics, Ursinus College,  Collegeville, PA 19426, USA"},{"name":"Arthur P. 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