{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T05:45:58Z","timestamp":1745300758028},"reference-count":6,"publisher":"World Scientific Pub Co Pte Lt","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int. J. Bifurcation Chaos"],"published-print":{"date-parts":[[2007,10]]},"abstract":"<jats:p> We propose the use of nonlinear electronic circuits to study synthetic gene regulation networks. Specifically, we have designed two electronic versions of a synthetic genetic clock, known as the \"repressilator,\" making use of appropriate electronic elements linked in the same way as the original biochemical system. We study the effects of coupling in a population of electronic repressilators, with the aim of observing coherent oscillations of the whole population. With these results, we show that this kind of nonlinear circuits can be helpful in the design and understanding of synthetic genetic networks. <\/jats:p>","DOI":"10.1142\/s0218127407019275","type":"journal-article","created":{"date-parts":[[2008,1,15]],"date-time":"2008-01-15T06:02:14Z","timestamp":1200376934000},"page":"3507-3511","source":"Crossref","is-referenced-by-count":6,"title":["ELECTRONIC DESIGN OF SYNTHETIC GENETIC NETWORKS"],"prefix":"10.1142","volume":"17","author":[{"given":"JAVIER M.","family":"BULD\u00da","sequence":"first","affiliation":[{"name":"Nonlinear Dynamics and Chaos Group, Departamento de F\u00edsica, Universidad Rey Juan Carlos, Tulip\u00e1n s\/n, 28933 M\u00f3stoles, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JORDI","family":"GARC\u00cdA-OJALVO","sequence":"additional","affiliation":[{"name":"Departament de F\u00edsica i Enginyeria Nuclear, Univ. Polit\u00e8cnica de Catalunya, Colom 11, 08222 Terrassa, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ALEXANDRE","family":"WAGEMAKERS","sequence":"additional","affiliation":[{"name":"Nonlinear Dynamics and Chaos Group, Departamento de F\u00edsica, Universidad Rey Juan Carlos, Tulip\u00e1n s\/n, 28933 M\u00f3stoles, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MIGUEL A. F.","family":"SANJU\u00c1N","sequence":"additional","affiliation":[{"name":"Nonlinear Dynamics and Chaos Group, Departamento de F\u00edsica, Universidad Rey Juan Carlos, Tulip\u00e1n s\/n, 28933 M\u00f3stoles, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2011,11,20]]},"reference":[{"key":"rf1","doi-asserted-by":"publisher","DOI":"10.1038\/35002125"},{"key":"rf2","volume-title":"Op Amps and Linear Integrates Circuits","author":"Fiore J. M.","year":"2000"},{"key":"rf3","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0307095101"},{"key":"rf4","doi-asserted-by":"publisher","DOI":"10.1038\/35002131"},{"key":"rf5","doi-asserted-by":"publisher","DOI":"10.1038\/nature01257"},{"key":"rf6","doi-asserted-by":"publisher","DOI":"10.1063\/1.1786683"}],"container-title":["International Journal of Bifurcation and Chaos"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.worldscientific.com\/doi\/pdf\/10.1142\/S0218127407019275","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,6]],"date-time":"2019-08-06T20:02:03Z","timestamp":1565121723000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.worldscientific.com\/doi\/abs\/10.1142\/S0218127407019275"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,10]]},"references-count":6,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2011,11,20]]},"published-print":{"date-parts":[[2007,10]]}},"alternative-id":["10.1142\/S0218127407019275"],"URL":"https:\/\/doi.org\/10.1142\/s0218127407019275","relation":{},"ISSN":["0218-1274","1793-6551"],"issn-type":[{"value":"0218-1274","type":"print"},{"value":"1793-6551","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,10]]}}}