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There are two main advantages of this regimen, i.e. it not only may delay the development of drug resistance, but also may reduce the duration of on-treatment time compared with the long-term continuous medication. Moreover, such an intermittent antiviral therapy can reduce the adverse side effects. Our theoretical model and computational results provide qualitative insight into the progression of HBV, and also a possible new therapy for HBV disease.<\/jats:p>","DOI":"10.1142\/s0218127415400118","type":"journal-article","created":{"date-parts":[[2015,7,16]],"date-time":"2015-07-16T11:23:03Z","timestamp":1437045783000},"page":"1540011","source":"Crossref","is-referenced-by-count":2,"title":["Dynamics of an HBV Model with Drug Resistance Under Intermittent Antiviral Therapy"],"prefix":"10.1142","volume":"25","author":[{"given":"Ben-Gong","family":"Zhang","sequence":"first","affiliation":[{"name":"School of Mathematics and Computer Science, Wuhan Textile University, Wuhan 430073, P. R. 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