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Numerical results show that diffusion can drive otherwise stable system into aperiodic behavior with sensitivity to initial conditions. We show that spatially induced chaos plays an important role in spatial pattern formation in heterogeneous environment. Spatiotemporal distributions of species have been simulated using the diffusivity assumptions realistic for natural eco-epidemic systems. We found that in heterogeneous environment, the temporal dynamics of both the species are drastically different and show chaotic behavior. It was also found that the instability observed in the model is due to spatial heterogeneity and diffusion-driven. Cumulative death rate of predator has an appreciable effect on model dynamics as the spatial distribution of all constituent populations exhibit significant changes when this model parameter is changed and it acts as a regularizing factor.<\/jats:p>","DOI":"10.1142\/s0218127416500048","type":"journal-article","created":{"date-parts":[[2016,2,19]],"date-time":"2016-02-19T06:18:57Z","timestamp":1455862737000},"page":"1650004","source":"Crossref","is-referenced-by-count":8,"title":["Disease Spread and Its Effect on Population Dynamics in Heterogeneous Environment"],"prefix":"10.1142","volume":"26","author":[{"given":"Ranjit Kumar","family":"Upadhyay","sequence":"first","affiliation":[{"name":"Department of Applied Mathematics, Indian School of Mines Dhanbad 826004, Jharkhand, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parimita","family":"Roy","sequence":"additional","affiliation":[{"name":"Department of Applied Mathematics, Indian School of Mines Dhanbad 826004, Jharkhand, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2016,2,18]]},"reference":[{"key":"S0218127416500048BIB001","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780198545996.001.0001","volume-title":"Infectious Diseases of Humans","volume":"1","author":"Anderson R. 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