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The TNM staging system as well as histologic subtypes classification were adopted as a reference. The VGG 16 network is applied to the PET\/CT images to extract the most relevant features from images. The obtained features are then transmitted to a three-branch classifier to specify Nodal (N), Tumor (T) and histologic subtypes classification. Experimental results demonstrated that our CNN model achieves good results in TN staging and histology classification. The proposed architecture classified the tumor size with a high accuracy of 0.94 and the area under the curve (AUC) of 0.97 when tested on the Lung-PET-CT-Dx dataset. It also has yielded high performance for N staging with an accuracy of 0.98. Besides, our approach has achieved better accuracy than state-of-the-art methods in histologic classification. <\/jats:p>","DOI":"10.1142\/s0219467824500402","type":"journal-article","created":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T06:48:53Z","timestamp":1689576533000},"source":"Crossref","is-referenced-by-count":5,"title":["Computer-Aided Classification of Cell Lung Cancer Via PET\/CT Images Using Convolutional Neural Network"],"prefix":"10.1142","volume":"24","author":[{"given":"Dhekra","family":"El Hamdi","sequence":"first","affiliation":[{"name":"Laboratoire d\u2019Informatique, Programmation Algorithmique et Heuristiques (LIPAH), Facult\u00e9 des sciences de Tunis, Universit\u00e9 de Tunis EL Manar, 1068, Tunis, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ines","family":"Elouedi","sequence":"additional","affiliation":[{"name":"Laboratoire d\u2019Informatique, Programmation Algorithmique et Heuristiques (LIPAH), Facult\u00e9 des sciences de Tunis, Universit\u00e9 de Tunis EL Manar, 1068, Tunis, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ihsen","family":"Slim","sequence":"additional","affiliation":[{"name":"Institut Salah Aza\u0131z, Rue Bab Saadoune, Tunis 1006, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2023,7,15]]},"reference":[{"key":"S0219467824500402BIB001","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21654"},{"key":"S0219467824500402BIB002","doi-asserted-by":"publisher","DOI":"10.1016\/j.molonc.2010.05.002"},{"key":"S0219467824500402BIB003","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3775"},{"key":"S0219467824500402BIB004","first-page":"S463","volume":"5","author":"Davidson M. 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