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This paper develops a theoretical framework and demonstrates mathematically that mating between the three different genotypic groups, namely: normal AA, carriers AS and sicklers SS, does not yield equal probabilities of having neonates of these classes. <\/jats:p>","DOI":"10.1142\/s0219525905000300","type":"journal-article","created":{"date-parts":[[2005,4,21]],"date-time":"2005-04-21T10:25:16Z","timestamp":1114079116000},"page":"1-5","source":"Crossref","is-referenced-by-count":2,"title":["EFFECTS OF SELECTIVE ADVANTAGE OF HbS OVER HbA IN THE TRANSMISSION DYNAMICS OF SICKLE CELL ANAEMIA"],"prefix":"10.1142","volume":"08","author":[{"given":"JEAN M.","family":"TCHUENCHE","sequence":"first","affiliation":[{"name":"Department of Mathematical Sciences, University of Agriculture, PMB 2240, Abeokuta, Nigeria"}]}],"member":"219","published-online":{"date-parts":[[2011,11,20]]},"reference":[{"key":"rf1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.1954.tb01261.x"},{"key":"rf2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.1971.tb00266.x"},{"key":"rf3","unstructured":"A. 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