{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T11:20:58Z","timestamp":1760008858429},"reference-count":35,"publisher":"World Scientific Pub Co Pte Ltd","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Advs. Complex Syst."],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:p>Microtubules (MTs) are cytoskeletal protein polymers orchestrating a host of important cellular functions including, but not limited to, cell support, cell division, cell motility and cell transport. We construct a toy-model of the MT lattice composed of classical vector Ising spins (dipole moments) representing the tubulin molecules, the building block of MTs. Nearest-neighbor (NN) and next-nearest-neighbor (NNN) interactions are considered within an anisotropic dielectric medium. As a consequence of the helical topology, certain spin orientations render the lattice frustrated with NN ferroelectric and NNN antiferroelectric bonds. Mapping the problem to a 2D Ising model and employing Monte Carlo methods we find that frozen clusters of spins exist at human physiological temperatures. This suggests a novel biological mechanism for storing information in living organisms, whereby the classical tubulin spin states become information bits and information gets stored in MTs in a way that is robust to thermal fluctuations.<\/jats:p>","DOI":"10.1142\/s0219525913500331","type":"journal-article","created":{"date-parts":[[2013,10,24]],"date-time":"2013-10-24T09:10:53Z","timestamp":1382605853000},"page":"1350033","source":"Crossref","is-referenced-by-count":1,"title":["PERSISTENT PATTERNS IN MICROTUBULE DIPOLE LATTICES"],"prefix":"10.1142","volume":"16","author":[{"given":"SHUBHENDU","family":"NANDI","sequence":"first","affiliation":[{"name":"Department of Physics, University of Miami, Coral Gables, Florida 33124, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"NEIL F.","family":"JOHNSON","sequence":"additional","affiliation":[{"name":"Department of Physics, University of Miami, Coral Gables, Florida 33124, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOSHUA L.","family":"COHN","sequence":"additional","affiliation":[{"name":"Department of Physics, University of Miami, Coral Gables, Florida 33124, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2014,4,9]]},"reference":[{"key":"rf1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2006.09.045"},{"key":"rf2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-5193(73)90233-6"},{"key":"rf3","doi-asserted-by":"publisher","DOI":"10.1038\/nature08917"},{"key":"rf4","doi-asserted-by":"publisher","DOI":"10.1038\/nature06433"},{"key":"rf5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1002421"},{"key":"rf6","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.66.011901"},{"key":"rf7","doi-asserted-by":"crossref","DOI":"10.1515\/9780691215051","volume-title":"Polyominoes: Puzzles, Patterns, Problems, and Packings","author":"Golomb S. 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