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Appearance and abundance of various transcription factor binding sites in the promoter region of the genes were studied. Through the combination of these techniques, we were able to identify 24 candidate genes involved in the SAR defense mechanism. The candidate genes fell into 2 highly resolved categories, each category showing significantly unique profiles of regulatory elements in their promoter regions. This study demonstrates the strength of such integration methods and suggests a broader application of this approach.<\/jats:p>","DOI":"10.1142\/s0219720004000776","type":"journal-article","created":{"date-parts":[[2004,12,3]],"date-time":"2004-12-03T11:55:19Z","timestamp":1102074919000},"page":"639-655","source":"Crossref","is-referenced-by-count":20,"title":["DISCOVERY OF FUNCTIONAL GENES FOR SYSTEMIC ACQUIRED RESISTANCE IN<i>ARABIDOPSIS THALIANA<\/i>THROUGH INTEGRATED DATA MINING"],"prefix":"10.1142","volume":"02","author":[{"given":"YOULIAN","family":"PAN","sequence":"first","affiliation":[{"name":"Institute for Information Technology, National Research Council Canada, 1200 Montreal Road, Bldg M-50, Ottawa, Ontario, Canada K1A 0R6, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JEFFREY D.","family":"PYLATUIK","sequence":"additional","affiliation":[{"name":"Plant Biotechnology Institute, National Research Council Canada, 110 Gymnasium Place, Saskatoon, Saskatchewan, Canada S7N 0W9, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JUNJUN","family":"OUYANG","sequence":"additional","affiliation":[{"name":"Institute for Information Technology, National Research Council Canada, 1200 Montreal Road, Bldg M-50, Ottawa, Ontario, Canada K1A 0R6, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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