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Scientific protocols designed to answer these questions can be run entirely on a computer. <\/jats:p><jats:p> Biological resources are often complementary, focused on different objects and reflecting various experts' points of view. Exploiting the richness and diversity of these resources is crucial for scientists. However, with the increase of resources, scientists have to face the problem of selecting sources and tools when interpreting their data. <\/jats:p><jats:p> In this paper, we analyze the way in which biologists express and implement scientific protocols, and we identify the requirements for a system which can guide scientists in constructing protocols to answer new biological questions. We present two such systems, BioNavigation and BioGuide dedicated to help scientists select resources by following suitable paths within the growing network of interconnected biological resources. <\/jats:p>","DOI":"10.1142\/s0219720006002375","type":"journal-article","created":{"date-parts":[[2006,11,9]],"date-time":"2006-11-09T11:10:26Z","timestamp":1163070626000},"page":"1069-1095","source":"Crossref","is-referenced-by-count":31,"title":["PATH-BASED SYSTEMS TO GUIDE SCIENTISTS IN THE MAZE OF BIOLOGICAL DATA SOURCES"],"prefix":"10.1142","volume":"04","author":[{"given":"SARAH","family":"COHEN-BOULAKIA","sequence":"first","affiliation":[{"name":"Department of Computer and Information Science, University of Pennsylvania, 3330 Walnut St, PA-19104 Philadelphia, USA"},{"name":"Laboratoire de Recherche en Informatique, CNRS UMR 8623, Universit\u00e9 Paris-Sud 11, 91405 Orsay, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SUSAN","family":"DAVIDSON","sequence":"additional","affiliation":[{"name":"Department of Computer and Information Science, University of Pennsylvania, 3330 Walnut St, PA-19104 Philadelphia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CHRISTINE","family":"FROIDEVAUX","sequence":"additional","affiliation":[{"name":"Laboratoire de Recherche en Informatique, CNRS UMR 8623, Universit\u00e9 Paris-Sud 11, 91405 Orsay, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ZO\u00c9","family":"LACROIX","sequence":"additional","affiliation":[{"name":"Arizona State University, Tempe AZ, USA"},{"name":"University of Maryland, College Park MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MARIA-ESTHER","family":"VIDAL","sequence":"additional","affiliation":[{"name":"Universidad Sim\u00f3n Bol\u00edvar, Caracas, Venezuela"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2011,11,21]]},"reference":[{"key":"rf1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/17.2.180"},{"key":"rf2","doi-asserted-by":"publisher","DOI":"10.1002\/asi.20136"},{"key":"rf3","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bth361"},{"key":"rf6","first-page":"i225","author":"Rowe A.","journal-title":"Bioinformatics"},{"key":"rf7","doi-asserted-by":"publisher","DOI":"10.1007\/11530084_24"},{"key":"rf8","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bth949"},{"key":"rf9","first-page":"80","author":"Greiner U.","journal-title":"Methods of Information in Medicine"},{"key":"rf12","first-page":"D3","volume":"34","author":"Galepin M. 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