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The prediction accuracies, using a collection of well-characterized transmembrane protein sequences and benchmarking sequences, suggest that the proposed algorithm performs reasonably well. An experiment was performed with a glutamate transporter homologue from Pyrococcus horikoshii. The predicted transmembrane regions of the five human glutamate transporter sequences and observations based on the computed likelihood are reported. <\/jats:p>","DOI":"10.1142\/s0219720007002667","type":"journal-article","created":{"date-parts":[[2007,8,9]],"date-time":"2007-08-09T20:32:00Z","timestamp":1186691520000},"page":"669-692","source":"Crossref","is-referenced-by-count":1,"title":["TRANSMEMBRANE STRUCTURE PREDICTIONS WITH HYDROPATHY INDEX\/CHARGE TWO-DIMENSIONAL TRAJECTORIES OF STOCHASTIC DYNAMICAL SYSTEMS"],"prefix":"10.1142","volume":"05","author":[{"given":"TAKASHI","family":"KABURAGI","sequence":"first","affiliation":[{"name":"Department of Electrical Engineering and Bioscience, Waseda University, 3-4-1 Ohkubo, Shinjuku-ku, Tokyo 169-8555, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"DAIGO","family":"MURAMATSU","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering and Bioscience, Waseda University, 3-4-1 Ohkubo, Shinjuku-ku, Tokyo 169-8555, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TAKASHI","family":"MATSUMOTO","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering and Bioscience, Waseda University, 3-4-1 Ohkubo, Shinjuku-ku, Tokyo 169-8555, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2011,11,21]]},"reference":[{"key":"rf1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-4889(99)00087-7"},{"key":"rf2","doi-asserted-by":"publisher","DOI":"10.1016\/S0955-0674(00)00219-2"},{"key":"rf3","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-4889(98)00057-3"},{"key":"rf4","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-6147(99)01366-8"},{"key":"rf5","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5460.1960"},{"key":"rf6","doi-asserted-by":"publisher","DOI":"10.1002\/pro.5560070420"},{"key":"rf7","doi-asserted-by":"publisher","DOI":"10.1016\/S1047-8477(03)00043-1"},{"key":"rf8","doi-asserted-by":"publisher","DOI":"10.1038\/nsb1101-923"},{"key":"rf9","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.2000.4315"},{"key":"rf10","first-page":"21","volume":"1","author":"Chen C. 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