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We are interested in creating a method that can detect the shared signature of a group of expression profiles, e.g. a group of samples from individuals with the same disease or a group of drugs that treat the same therapeutic indication. We have developed a novel Weighted Influence \u2014 Rank of Ranks (WIMRR) method, and we demonstrate its ability to produce both meaningful and reproducible group signatures.<\/jats:p>","DOI":"10.1142\/s0219720011005598","type":"journal-article","created":{"date-parts":[[2011,6,20]],"date-time":"2011-06-20T11:22:26Z","timestamp":1308568946000},"page":"431-451","source":"Crossref","is-referenced-by-count":4,"title":["A METHOD FOR THE DETECTION OF MEANINGFUL AND REPRODUCIBLE GROUP SIGNATURES FROM GENE EXPRESSION PROFILES"],"prefix":"10.1142","volume":"09","author":[{"given":"LOUIS","family":"LICAMELE","sequence":"first","affiliation":[{"name":"Computer Science Department, University of Maryland, AV Williams Bldg, Rm 3228, College Park, Maryland 20742, USA"},{"name":"Informatics Department, Vanda Pharmaceuticals Inc, 9605 Medical Center Drive, Suite 300, Rockville, Maryland 20850, USA"}]},{"given":"LISE","family":"GETOOR","sequence":"additional","affiliation":[{"name":"Computer Science Department, University of Maryland, AV Williams Bldg, Rm 3228, College Park, Maryland 20742, USA"}]}],"member":"219","published-online":{"date-parts":[[2011,11,21]]},"reference":[{"key":"rf1","doi-asserted-by":"publisher","DOI":"10.1038\/4427"},{"key":"rf2","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1746"},{"key":"rf3","doi-asserted-by":"publisher","DOI":"10.1126\/science.306.5696.630"},{"key":"rf4","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkg763"},{"key":"rf5","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0601231103"},{"key":"rf6","doi-asserted-by":"publisher","DOI":"10.1038\/nbt965"},{"key":"rf7","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3233\/ISB-2009-0387","volume":"9","author":"Zhang W.","journal-title":"In. 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