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We mainly focus on the parameter estimation and sensitivity analysis problems and survey the current methods for tackling them. In this context we also highlight a recently developed probabilistic approximation technique using which these two problems can be considerably simplified.<\/jats:p>","DOI":"10.1142\/s0219720012310014","type":"journal-article","created":{"date-parts":[[2012,4,4]],"date-time":"2012-04-04T09:03:58Z","timestamp":1333530238000},"page":"1231001","source":"Crossref","is-referenced-by-count":15,"title":["MODELING AND ANALYSIS OF BIOPATHWAYS DYNAMICS"],"prefix":"10.1142","volume":"10","author":[{"given":"BING","family":"LIU","sequence":"first","affiliation":[{"name":"Department of Computer Science, National University of Singapore, Computing 1, 13 Computing Drive, Singapore 117417, Singapore"}]},{"given":"P. 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