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In this article, we propose a semi alignment-free method of sequence comparison based on word frequency distributions, in which we partially use the alignment to measure word frequencies along with the idea of fuzzy set theory. Experiments with ten bacterial genome sequences demonstrated that the fuzzy measurements has the effect that facilitates discrimination between close relatives and distant relatives. <\/jats:p>","DOI":"10.1142\/s021972001450019x","type":"journal-article","created":{"date-parts":[[2014,7,11]],"date-time":"2014-07-11T06:19:23Z","timestamp":1405059563000},"page":"1450019","source":"Crossref","is-referenced-by-count":0,"title":["Measurement of word frequencies in genomic DNA sequences based on partial alignment and fuzzy set"],"prefix":"10.1142","volume":"12","author":[{"given":"Fumiya","family":"Shida","sequence":"first","affiliation":[{"name":"Graduate School of Science and Technology, Hirosaki University, 3 Bunkyo-cho, Hirosaki, Aomori 036-8561, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Mizuta","sequence":"additional","affiliation":[{"name":"Graduate School of Science and Technology, Hirosaki University, 3 Bunkyo-cho, Hirosaki, Aomori 036-8561, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2014,8,25]]},"reference":[{"key":"rf1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(70)90057-4"},{"key":"rf2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(81)90087-5"},{"key":"rf3","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-11-224"},{"key":"rf4","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2004-5-2-r12"},{"key":"rf5","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/4.2.105"},{"key":"rf6","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btg005"},{"key":"rf7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijar.2007.03.011"},{"key":"rf8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2012.10.010"},{"key":"rf9","doi-asserted-by":"publisher","DOI":"10.1007\/s10910-011-9811-x"},{"key":"rf10","first-page":"67","volume":"106","author":"Aita T.","year":"2011","journal-title":"Bio. 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