{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T22:25:50Z","timestamp":1765232750783,"version":"3.37.3"},"reference-count":31,"publisher":"World Scientific Pub Co Pte Ltd","issue":"04","funder":[{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LGG19F030013"],"award-info":[{"award-number":["LGG19F030013"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LGF18F010007"],"award-info":[{"award-number":["LGF18F010007"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Special Funds for Information Development in Shanghai","award":["201801050"],"award-info":[{"award-number":["201801050"]}]},{"name":"Scientific research project of Zhejiang Provincial Department of Education","award":["Y201533647"],"award-info":[{"award-number":["Y201533647"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61602417"],"award-info":[{"award-number":["61602417"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int. J. Human. Robot."],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:p>Epilepsy is caused by sudden abnormal discharges of neurons in the brain. This paper constructs an automatic seizure detection system, which combines the predicting result of multi-domain feature with the predicting result of spike rate feature to detect the occurrence of epileptic seizures. After segmenting EEG data into 5[Formula: see text]s with 80% overlap epochs, the paper extracts time domain features, frequency domain features and hurst exponents (HE) from each epoch and these features are reduced by linear discriminant analysis (LDA) to be input parameters of the random forest (RF) classifier, which provides classification of the EEG epochs concerning the existence of seizures. In parallel, the paper extracts spikes from EEG data with morphological filter and calculates the spike rate to determine whether there is seizure. Then the results obtained by these two methods are merged as the final detection result. The paper shows that the accuracy (AC), sensitivity (SE), specificity (SP) and the false positive ratio based on event (FPRE) obtained by hybrid method are 98.94%, 76.60%, 98.99% and 2.43 times\/h, respectively. Finally, the paper applies the seizure detection method to do seizure warning and recording to help the family member to take care of the patients and the doctor to adjust the antiepileptic drugs (AEDs).<\/jats:p>","DOI":"10.1142\/s0219843619500166","type":"journal-article","created":{"date-parts":[[2019,6,27]],"date-time":"2019-06-27T08:20:05Z","timestamp":1561623605000},"page":"1950016","source":"Crossref","is-referenced-by-count":6,"title":["Epileptic Seizure Detection System Based on Multi-Domain Feature and Spike Feature of EEG"],"prefix":"10.1142","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6954-6587","authenticated-orcid":false,"given":"Duanpo","family":"Wu","sequence":"first","affiliation":[{"name":"School of Communication Engineering, Hangzhou Dianzi University, Xiasha Higher Education Zone, Hangzhou 310018, P. R. China"},{"name":"Zhejiang Provincial Key Laboratory of Information Processing, Communication and Networking, Zhejiang, Hangzhou 310027, P. R. China"},{"name":"Department of Algorithm, Hangzhou Neuro Science and Technology Co., Ltd., Room 2601, Huaye Building, Hangzhou 310051, P. R. China"}]},{"given":"Zimeng","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Communication Engineering, Hangzhou Dianzi University, Xiasha Higher Education Zone, Hangzhou 310018, P. R. China"}]},{"given":"Hong","family":"Huang","sequence":"additional","affiliation":[{"name":"Pharmacy Department, Huaxi Second Hospital, No. 20, Section 3, Renmin South Road, Jinjiang District, Chengdu 610041, P. R. China"}]},{"given":"Guangsheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Shuyang People\u2019s Hospital, Xuzhou Medical University, No. 9 Yingbin Avenue, Yucheng Town, Xuzhou 223000, P. R. China"}]},{"given":"Junbiao","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Algorithm, Hangzhou Neuro Science and Technology Co., Ltd., Room 2601, Huaye Building, Hangzhou 310051, P. R. China"}]},{"given":"Chenyi","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Algorithm, Hangzhou Neuro Science and Technology Co., Ltd., Room 2601, Huaye Building, Hangzhou 310051, P. R. China"}]},{"given":"Weifeng","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Algorithm, Hangzhou Neuro Science and Technology Co., Ltd., Room 2601, Huaye Building, Hangzhou 310051, P. R. China"}]}],"member":"219","published-online":{"date-parts":[[2019,9,27]]},"reference":[{"doi-asserted-by":"publisher","key":"S0219843619500166BIB001","DOI":"10.2147\/NDT.S167841"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB002","DOI":"10.1016\/j.knosys.2013.02.014"},{"issue":"9","key":"S0219843619500166BIB003","first-page":"147","volume":"54","author":"Ghoshdastidar S.","year":"2007","journal-title":"IEEE Trans. Bio-Med. Eng."},{"issue":"9","key":"S0219843619500166BIB004","volume":"54","author":"Acharya U. R.","year":"2017","journal-title":"Comput. Biol. Med."},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB005","DOI":"10.3390\/s18020335"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB006","DOI":"10.3390\/brainsci7060058"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB007","DOI":"10.1016\/j.bspc.2016.10.001"},{"key":"S0219843619500166BIB008","first-page":"1","volume":"99","author":"Feng L.","year":"2018","journal-title":"IEEE Trans. Biomed. Circ. Syst."},{"issue":"3","key":"S0219843619500166BIB009","first-page":"1","volume":"10","author":"Chakraborti S.","year":"2018","journal-title":"Int. J. Inf. Technol."},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB010","DOI":"10.1016\/j.bbe.2018.03.007"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB011","DOI":"10.2174\/1573405613666161227154355"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB012","DOI":"10.1155\/2018\/5812872"},{"issue":"1","key":"S0219843619500166BIB013","first-page":"123","volume":"37","author":"Chen G.","year":"2018","journal-title":"Int. J. Biomed. Imag."},{"issue":"3","key":"S0219843619500166BIB014","first-page":"81","volume":"2","author":"Khan Y. U.","year":"2012","journal-title":"Int. J. Embed. Syst. Appl."},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB015","DOI":"10.1109\/ACCESS.2019.2904949"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB016","DOI":"10.1016\/j.seizure.2017.05.018"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB017","DOI":"10.1186\/1743-0003-5-10"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB018","DOI":"10.1080\/03091902.2017.1394390"},{"issue":"6","key":"S0219843619500166BIB019","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1109\/TNSRE.2013.2282153","volume":"21","author":"Li S.","year":"2012","journal-title":"IEEE Trans. Neural Syst. Rehabil. Eng."},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB020","DOI":"10.1016\/j.pscychresns.2018.02.001"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB021","DOI":"10.1016\/j.bspc.2017.07.022"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB022","DOI":"10.1016\/j.bspc.2015.01.002"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB023","DOI":"10.1166\/jmihi.2016.1736"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB024","DOI":"10.1142\/S0219843616500092"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB025","DOI":"10.1023\/A:1010933404324"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB026","DOI":"10.1142\/S0219843612500259"},{"issue":"3","key":"S0219843619500166BIB027","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1109\/TNSRE.2015.2505238","volume":"24","author":"Zabihi M.","journal-title":"IEEE Trans. Neural Syst. Rehabil. Eng."},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB028","DOI":"10.1016\/j.knosys.2016.11.023"},{"doi-asserted-by":"publisher","key":"S0219843619500166BIB029","DOI":"10.1016\/j.neucom.2017.02.053"},{"issue":"103","key":"S0219843619500166BIB030","first-page":"913","volume":"29","author":"Selvakumari R. S.","year":"2018","journal-title":"Ecography"},{"key":"S0219843619500166BIB031","first-page":"92","volume-title":"2018 IEEE EMBS Int. Conf.","author":"Tsiouris K. M.","year":"2018"}],"container-title":["International Journal of Humanoid Robotics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.worldscientific.com\/doi\/pdf\/10.1142\/S0219843619500166","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,8]],"date-time":"2021-01-08T04:23:05Z","timestamp":1610079785000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.worldscientific.com\/doi\/abs\/10.1142\/S0219843619500166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":31,"journal-issue":{"issue":"04","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.1142\/S0219843619500166"],"URL":"https:\/\/doi.org\/10.1142\/s0219843619500166","relation":{},"ISSN":["0219-8436","1793-6942"],"issn-type":[{"type":"print","value":"0219-8436"},{"type":"electronic","value":"1793-6942"}],"subject":[],"published":{"date-parts":[[2019,8]]}}}