{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T08:19:17Z","timestamp":1778660357413,"version":"3.51.4"},"reference-count":9,"publisher":"World Scientific Pub Co Pte Lt","issue":"03n04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Chin. Med."],"published-print":{"date-parts":[[2001,1]]},"abstract":"<jats:p> Jiawey Siwu (JS) is a modified formula of Siwu with the addition of Ginseng Radix and Eucommiae Cortex. We studied the CNS effect of JS on pentobarbital-induced hypnosis in ICR mice after acute oral administration. We also investigated the motor activity and exercise performance effects of JS in SD rats after subchronic (12 days) and chronic (8 weeks) oral administration with an activity cage and rotarod, respectively. The duration of pentobarbital-induced hypnesis was significantly decreased in mice after acute oral administration of 0.21, 1.05 or 4.2 g\/kg JS. The time of ambulatory activity and time on the rotarod significantly increased in rats after subchronic and chronic oral administration of 1.05 g\/kg JS, respectively. These results indicate that JS potentially increased the excitability of the CNS in mice, as well as increasing motor activity and physical endurance in rats. <\/jats:p>","DOI":"10.1142\/s0192415x01000538","type":"journal-article","created":{"date-parts":[[2003,10,28]],"date-time":"2003-10-28T04:41:09Z","timestamp":1067316069000},"page":"509-516","source":"Crossref","is-referenced-by-count":4,"title":["Effects of Jiawey Siwu on Rat Activity"],"prefix":"10.1142","volume":"29","author":[{"given":"Zhi-Hong","family":"Jian","sequence":"first","affiliation":[{"name":"School of Medicine, National Yang-Ming University, Taipei 112, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chien-Chih","family":"Chen","sequence":"additional","affiliation":[{"name":"National Research Institute of Chinese Medicine, Taipei 112, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsi-Yen","family":"Lu","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih-Pang","family":"Chu","sequence":"additional","affiliation":[{"name":"School of Medicine, National Taiwan University, Taipei 100, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yee-Yung","family":"Ng","sequence":"additional","affiliation":[{"name":"School of Medicine, National Yang-Ming University, Taipei 112, Taiwan"},{"name":"Division of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sue","family":"Yu","sequence":"additional","affiliation":[{"name":"National Research Institute of Chinese Medicine, Taipei 112, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2012,4,5]]},"reference":[{"key":"p_2","first-page":"870","volume":"105","author":"Chen K.J.","year":"1992","journal-title":"Chinese Medical Journal"},{"key":"p_5","first-page":"483","volume":"23","author":"He D.C.","year":"1996","journal-title":"Liaoning Journal of Traditional Chinese Medicine"},{"key":"p_6","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-962058"},{"key":"p_7","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.17.1282"},{"key":"p_8","first-page":"241","volume":"16","author":"Li T.J.","year":"1995","journal-title":"Academic Journal of Second Military Medical University"},{"key":"p_9","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.23.54"},{"key":"p_12","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1123\/ijsn.6.3.263","volume":"6","author":"Morris A.C.","year":"1996","journal-title":"International J. 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Biochem."},{"key":"p_14","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.27.509"}],"container-title":["The American Journal of Chinese Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.worldscientific.com\/doi\/pdf\/10.1142\/S0192415X01000538","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,6]],"date-time":"2019-08-06T20:19:44Z","timestamp":1565122784000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.worldscientific.com\/doi\/abs\/10.1142\/S0192415X01000538"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,1]]},"references-count":9,"journal-issue":{"issue":"03n04","published-online":{"date-parts":[[2012,4,5]]},"published-print":{"date-parts":[[2001,1]]}},"alternative-id":["10.1142\/S0192415X01000538"],"URL":"https:\/\/doi.org\/10.1142\/s0192415x01000538","relation":{},"ISSN":["0192-415X","1793-6853"],"issn-type":[{"value":"0192-415X","type":"print"},{"value":"1793-6853","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,1]]}}}