{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T12:29:52Z","timestamp":1760099392348},"reference-count":15,"publisher":"World Scientific Pub Co Pte Lt","issue":"04","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Chin. Med."],"published-print":{"date-parts":[[2003,1]]},"abstract":"<jats:p> Shao-Fu-Zhu-Yu-Tang (SFZYT) is reportedly beneficial to sperm. In this study, we examined sperm acrosomal activity and serum free radical changes to evaluate the possible mechanism of SFZYT. A clinical study evaluated the sperm count and motility in 36 patients with chronic prostatitis before and after treatment for 60 days. The results revealed a significant increase in sperm motility after treatment as evaluated by computer-assisted semen analysis (17.27 \u00b1 9.00 versus 28.29 \u00b1 10.00, p &lt; 0.01). An increase in sperm quantity and quality was observed by count and morphology with a high-powered intravital microscope. To gain an understanding of the mechanisms that caused this effect, we assessed sperm acrosin activity levels before (10.6 \u03bc lu \/10<jats:sup>6<\/jats:sup>) and after medication (28.6 \u03bc lu \/10<jats:sup>6<\/jats:sup>)( p &lt; 0.01). The levels of the free radicals was relatively higher before medication, 2144, compared to a normal value of 780 after medication ( p &lt; 0.01). In conclusion, SFZYT increased the motility and quality of human semen and this increase is related to an increase in sperm acrosin activity. SFZYT also works as a sperm antioxidant and antiaging agent. <\/jats:p>","DOI":"10.1142\/s0192415x03001223","type":"journal-article","created":{"date-parts":[[2003,10,6]],"date-time":"2003-10-06T11:00:00Z","timestamp":1065438000000},"page":"573-579","source":"Crossref","is-referenced-by-count":14,"title":["Effects of Shao-Fu-Zhu-Yu-Tang on Motility of Human Sperm"],"prefix":"10.1142","volume":"31","author":[{"given":"Ching-Chiang","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Urology, China Medical University Hospital, Taichung 400, Taiwan, R.O.C."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung-Chou","family":"Chen","sequence":"additional","affiliation":[{"name":"Graduate Institute of Chinese Pharmaceutical Sciences, China Medical University, Taichung 400, Taiwan, R.O.C."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guang-Wei","family":"Chen","sequence":"additional","affiliation":[{"name":"Graduate Institute of Chinese Pharmaceutical Sciences, China Medical University, Taichung 400, Taiwan, R.O.C."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Shuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Departments of Nutrition and China Medical University, Taichung 400, Taiwan, R.O.C."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.G.","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Microbiology, China Medical University, No.91 Hsueh-Shih Road, Taichung 400, Taiwan, R.O.C."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2012,4,5]]},"reference":[{"key":"rf1","first-page":"97","volume":"27","author":"Asowwal A.","journal-title":"Arch. 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