{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T15:14:09Z","timestamp":1764688449471},"reference-count":19,"publisher":"World Scientific Pub Co Pte Lt","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Chin. Med."],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:p> This study was to evaluate the clinical efficacy of Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in), a Japanese traditional herbal medicine, in stabilizing postpartum psychological state. We enrolled 268 women who had a normal delivery in Osaka Medical College Hospital or its affiliated clinics and randomly assigned them to the following two groups: a group of 134 women who received Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) at a dose of 6.0 g\/day and another group of 134 women without Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) (control group). We observed 2.06-fold and 1.67-fold higher incidences of depressive mood and nervousness, respectively, after delivery in the control group than in the Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) group. Within 3 weeks of postpartum, there was a significant difference in the incidences of maternity blues between the Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) group (15.7%; 21\/134) and the control group (32.1%; 43\/134) (p=0.0195). No adverse effects were observed in this study. The results of this study demonstrate the beneficial clinical effects of Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) in stabilizing psychological state in the postpartum period. <\/jats:p><jats:p> Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) can be expected to improve the mental health of women in the postpartum period and prevent maternity blues. <\/jats:p>","DOI":"10.1142\/s0192415x05002710","type":"journal-article","created":{"date-parts":[[2005,3,31]],"date-time":"2005-03-31T12:25:00Z","timestamp":1112271900000},"page":"117-126","source":"Crossref","is-referenced-by-count":12,"title":["Efficacy of the Kampo Medicine Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in), a Traditional Herbal Medicine, in the Treatment of Maternity Blues Syndrome in the Postpartum Period"],"prefix":"10.1142","volume":"33","author":[{"given":"Takahisa","family":"Ushiroyama","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology,  Osaka Medical College, Takatsuki, Osaka 568-8686, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kou","family":"Sakuma","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology,  Osaka Medical College, Takatsuki, Osaka 568-8686, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minoru","family":"Ueki","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology,  Osaka Medical College, Takatsuki, Osaka 568-8686, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2012,4,10]]},"reference":[{"key":"rf1","doi-asserted-by":"publisher","DOI":"10.1097\/00006199-200109000-00004"},{"key":"rf2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.150.6.782"},{"key":"rf3","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.121.6.659"},{"key":"rf4","doi-asserted-by":"publisher","DOI":"10.3109\/00048678809161211"},{"key":"rf5","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.308.6934.949"},{"key":"rf6","doi-asserted-by":"publisher","DOI":"10.1007\/BF00802048"},{"key":"rf7","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1093\/hsw\/17.3.192","volume":"17","author":"Millis J. B.","journal-title":"Health Soc. Work"},{"key":"rf8","doi-asserted-by":"publisher","DOI":"10.1159\/000010011"},{"key":"rf9","first-page":"193","volume":"113","author":"Murray J. B.","journal-title":"Genet. Soc. Gen. Psycho. Monogr."},{"key":"rf10","doi-asserted-by":"publisher","DOI":"10.1046\/j.0902-4441.2000.ap90075.x"},{"key":"rf11","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.128.4.379"},{"key":"rf12","first-page":"525","volume":"74","author":"Okano T.","journal-title":"Arch. Psychiatry Diagn. Clin. Eval."},{"key":"rf13","first-page":"80","volume":"54","author":"Sakuma K.","journal-title":"Adv. Obstet. Gynecol."},{"key":"rf14","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(02)00091-7"},{"key":"rf15","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(80)90038-0"},{"key":"rf16","first-page":"150","volume":"20","author":"Ushiroyama T.","journal-title":"J. Tradit. 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