{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T17:30:50Z","timestamp":1696527050981},"reference-count":34,"publisher":"World Scientific Pub Co Pte Ltd","issue":"06","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Chin. Med."],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:p>To evaluate the effect of gingko biloba (EGb) on diethylstilbestrol (DES) induced testicle injury in mice. Fifty male mice were divided into a control group (A), DES group (B), and 3 EGb groups (C, D, E). The EGb-treated groups received peritoneal EGb at 8.75 (C), 17.5 (D), 35 mg\/kg (E) BW daily for 7 days. The control group was given equivalent amount of normal saline. The mice in groups B, C, D and E were injected hypodermically with DES at 40 mg\/kg BW daily 4 hours after the first herbal administration, while the control was given olive oil. Compared with DES group, the testis coefficients-relative testicular weight increased in the three EGb-treated groups. No significant difference was observed in epididymis coefficients. Lipid peroxidation status and antioxidant enzyme activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) were significantly elevated in testes of EGb-treated groups. Lactate dehydrogenase (LDH) activities and malonaldehyde (MDA) contents were significantly decreased in testes of the EGb groups. The results indicate that EGb protects the testis from diethylstilbestrol-induced injury.<\/jats:p>","DOI":"10.1142\/s0192415x08006478","type":"journal-article","created":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T11:44:17Z","timestamp":1228131857000},"page":"1135-1144","source":"Crossref","is-referenced-by-count":6,"title":["Effects of Ginkgo Biloba on Testicle Injury Induced by Diethylstilbestrol in Mice"],"prefix":"10.1142","volume":"36","author":[{"given":"Wei","family":"Wang","sequence":"first","affiliation":[{"name":"College of Animal Science and Veterinary Medicine, Agricultural University of Hebei, Baoding 071001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiu-Hui","family":"Zhong","sequence":"additional","affiliation":[{"name":"College of Animal Science and Veterinary Medicine, Agricultural University of Hebei, Baoding 071001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aituan","family":"Ma","sequence":"additional","affiliation":[{"name":"College of Animal Science and Veterinary Medicine, Agricultural University of Hebei, Baoding 071001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanyu","family":"Shi","sequence":"additional","affiliation":[{"name":"College of Animal Science and Veterinary Medicine, Agricultural University of Hebei, Baoding 071001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Si","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Animal Science and Veterinary Medicine, Agricultural University of Hebei, Baoding 071001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuzhi","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Animal Science and Veterinary Medicine, Agricultural University of Hebei, Baoding 071001, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2012,4,5]]},"reference":[{"key":"rf1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2005.12.026"},{"key":"rf2","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(02)04948-8"},{"key":"rf3","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-3-67"},{"key":"rf4","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(99)00173-2"},{"key":"rf5","first-page":"1161","volume":"163","author":"Chang W. 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