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More than 210 chemical constituents have been isolated and identified from Patrinia plants, especially P. scabiosaefolia Fisch., P. scabra Bunge, P. villosa Juss., P. heterophylla Bunge and P. rupestris(Pall.) Juss[Formula: see text] Of these compounds, triterpenoids and saponins, iridoids, flavonoids, and lignans are the major or active constituents. Both in vitro and in vivo studies have indicated that some monomer compounds and crude extracts from the genus Patrinia possess wide pharmacological activities, including antitumor, anti-inflammatory, antibacterial, and antiviral effects. In addition, they have been shown to have valuable and positive effects on the immune and nervous system in experimental animals. There are also some reports on the clinical uses and toxicity of these species. However, few reports have been published concerning the material identification or quality control of Patrinia species, and the clinical uses and toxic effects of these plants are relatively sparse. More attention must be given to these issues.<\/jats:p>","DOI":"10.1142\/s0192415x17500379","type":"journal-article","created":{"date-parts":[[2017,6,9]],"date-time":"2017-06-09T01:48:02Z","timestamp":1496972882000},"page":"637-666","source":"Crossref","is-referenced-by-count":45,"title":["The Genus<i>Patrinia<\/i>: A Review of Traditional Uses, Phytochemical and Pharmacological Studies"],"prefix":"10.1142","volume":"45","author":[{"given":"Xirui","family":"He","sequence":"first","affiliation":[{"name":"Honghui Hospital, Xi\u2019an Jiaotong University College of Medicine, Xi\u2019an 710054, P. R. China"},{"name":"Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi\u2019an, 710069, P. R. 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