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Study results indicated that DSs significantly relieved pain in FM (SMD 1.23; 95% CI 0.02\u20132.43, P = 0.046) but did not improve quality of life (QoL) (SMD 0.73; 95% CI \u22120.07\u20131.53, P = 0.075) in the data. Adverse events of DSs varied from mild to severe, with the most common being gastrointestinal symptoms and androgenic side effects in 5.7% and 3.9% of patients, respectively. More well-designed RCTs are required in the future. The protocol for this review has been published on PROSPERO (CRD42020149941).<\/jats:p>","DOI":"10.1142\/s0192415x22500495","type":"journal-article","created":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T07:53:00Z","timestamp":1654069980000},"page":"1197-1218","source":"Crossref","is-referenced-by-count":4,"title":["Dietary Supplements for Pain Relief in Patients with Fibromyalgia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials"],"prefix":"10.1142","volume":"50","author":[{"given":"Kia Teng","family":"Lim","sequence":"first","affiliation":[{"name":"Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kia Hui","family":"Lim","sequence":"additional","affiliation":[{"name":"Yong Loo Lin School of Medicine, National University of Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Formula-pattern Research Centre, School of Traditional Chinese Medicine, Jinan University Guangzhou, Guangdong Province 510632, P. 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