{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T13:55:09Z","timestamp":1781013309390,"version":"3.54.1"},"reference-count":68,"publisher":"World Scientific Pub Co Pte Ltd","issue":"08","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Chin. Med."],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p> Parkinson\u2019s disease (PD) is a progressive neurodegenerative disorder without a definitive cure. Oriental exercises (OEs) have emerged as a complementary and alternative therapy for PD, but their efficacy in ameliorating non-motor symptoms (NMS) and quality of life (QOL) remains uncertain. This systematic review and meta-analysis actively investigated the efficacy of OEs in addressing NMS and enhancing QOL and sought to offer recommendations for optimal OE regimens for PD patients. By analyzing 30 controlled trials involving 2029 participants, we found that OEs significantly improved cognitive function, neuropsychiatric symptoms, and QOL compared to control groups. Specifically, significant improvements were observed in several outcome measures: Parkinson\u2019s Disease Questionnaire (PDQ) [MD: [Formula: see text]3.67, 95% CI: [Formula: see text]5.72\u2013[Formula: see text]1.63, [Formula: see text], [Formula: see text]%], Parkinson\u2019s Disease Non-Motor Symptom Questionnaire (NMSQ) [MD: [Formula: see text]2.34, 95% CI: [Formula: see text]4.67\u2013[Formula: see text]0.01, [Formula: see text], [Formula: see text]%], Montreal Cognitive Assessment (MoCA) [MD: 1.75, 95% CI: 1.46\u20132.03, [Formula: see text], [Formula: see text]%], Stroop Color and Word Test (SCWT) [MD: 0.87, 95% CI: 0.49\u20131.24, [Formula: see text], [Formula: see text]%], Frontal Assessment Battery (FAB) [MD: 1.49, 95% CI: 1.16\u20131.81, [Formula: see text], [Formula: see text]%], Hamilton Depression Scale (HAMD) [MD: [Formula: see text]4.27, 95% CI: [Formula: see text]6.85\u2013[Formula: see text]1.69, [Formula: see text], [Formula: see text]%], Hamilton Anxiety Scale (HAMA) [MD: [Formula: see text]0.24, 95% CI: [Formula: see text]0.32\u2013[Formula: see text]0.16, [Formula: see text], [Formula: see text]%], and the Symptom Checklist-90 (SCL-90) [MD: [Formula: see text]0.37, 95% CI: [Formula: see text]0.48\u2013[Formula: see text]0.25, [Formula: see text], [Formula: see text]%]. Our findings provide compelling evidence for the potential benefits of OEs in managing NMS and improving QOL in PD patients. To optimize outcomes, we recommend customizing OE regimens based on individual clinical phenotypes, and to validate these results we emphasize the need for rigorous, large-scale studies. <\/jats:p>","DOI":"10.1142\/s0192415x24500861","type":"journal-article","created":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T08:40:54Z","timestamp":1735202454000},"page":"2233-2254","source":"Crossref","is-referenced-by-count":5,"title":["Efficacy of Oriental Exercises for Non-Motor Symptoms and Quality of Life in Parkinson\u2019s Disease: A Systematic Review and Meta-Analysis"],"prefix":"10.1142","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9725-4312","authenticated-orcid":false,"given":"Wanqing","family":"Peng","sequence":"first","affiliation":[{"name":"The First Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510000, Guangdong, P.\u00a0R.\u00a0China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2093-2393","authenticated-orcid":false,"given":"Renhui","family":"Zhao","sequence":"additional","affiliation":[{"name":"The First Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510000, Guangdong, P.\u00a0R.\u00a0China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9016-1471","authenticated-orcid":false,"given":"Ziting","family":"Huang","sequence":"additional","affiliation":[{"name":"The First Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510000, Guangdong, P.\u00a0R.\u00a0China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6602-4916","authenticated-orcid":false,"given":"Jingpei","family":"Zhou","sequence":"additional","affiliation":[{"name":"The First Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510000, Guangdong, P.\u00a0R.\u00a0China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9716-4226","authenticated-orcid":false,"given":"Quan","family":"Sun","sequence":"additional","affiliation":[{"name":"The First Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510000, Guangdong, P.\u00a0R.\u00a0China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8405-9904","authenticated-orcid":false,"given":"Ziyuan","family":"Li","sequence":"additional","affiliation":[{"name":"The First Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510000, Guangdong, P.\u00a0R.\u00a0China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5360-7154","authenticated-orcid":false,"given":"Xinyu","family":"Li","sequence":"additional","affiliation":[{"name":"The First Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510000, Guangdong, P.\u00a0R.\u00a0China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8718-8959","authenticated-orcid":false,"given":"Jinyan","family":"Yu","sequence":"additional","affiliation":[{"name":"The First Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510000, Guangdong, P.\u00a0R.\u00a0China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7119-8304","authenticated-orcid":false,"given":"Nanbu","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong, P.\u00a0R.\u00a0China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7086-0119","authenticated-orcid":false,"given":"Zhenhu","family":"Chen","sequence":"additional","affiliation":[{"name":"Acupuncture and Rehabilitation Centre, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong, P.\u00a0R.\u00a0China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"219","published-online":{"date-parts":[[2024,12,24]]},"reference":[{"key":"S0192415X24500861BIB001","doi-asserted-by":"publisher","DOI":"10.1186\/s13020-019-0225-1"},{"key":"S0192415X24500861BIB002","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.22360"},{"key":"S0192415X24500861BIB003","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27902"},{"key":"S0192415X24500861BIB004","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2016.12.060"},{"key":"S0192415X24500861BIB005","doi-asserted-by":"publisher","DOI":"10.4103\/aian.AIAN_169_18"},{"key":"S0192415X24500861BIB006","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-016-1517-6"},{"key":"S0192415X24500861BIB007","first-page":"231","volume":"42","author":"Burini D.","year":"2006","journal-title":"Eura. Medicophys."},{"key":"S0192415X24500861BIB008","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-1331.9.s3.6.x"},{"key":"S0192415X24500861BIB009","first-page":"1087","volume":"27","author":"Cao H.H.","year":"2021","journal-title":"Chin. J. Rehabil. Theor. Pract."},{"key":"S0192415X24500861BIB010","doi-asserted-by":"publisher","DOI":"10.3727\/096368916X694238"},{"key":"S0192415X24500861BIB011","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22868"},{"key":"S0192415X24500861BIB012","doi-asserted-by":"crossref","first-page":"e0135932","DOI":"10.1371\/journal.pone.0135932","volume":"10","author":"Chen B.L.","year":"2015","journal-title":"PLoS One"},{"key":"S0192415X24500861BIB013","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2013.9.4.237"},{"key":"S0192415X24500861BIB014","first-page":"19","volume":"23","author":"Ding L.","year":"2023","journal-title":"Shanghai Nurs. J."},{"key":"S0192415X24500861BIB015","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2023.1290471"},{"key":"S0192415X24500861BIB016","first-page":"143","volume":"36","author":"Fan J.","year":"2017","journal-title":"Chin. J. Sports Med."},{"key":"S0192415X24500861BIB017","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)01429-0"},{"key":"S0192415X24500861BIB018","first-page":"1684","volume":"31","author":"Guan X.","year":"2016","journal-title":"J. Adv. Nurs."},{"key":"S0192415X24500861BIB019","first-page":"1538","volume":"39","author":"Guan X.","year":"2016","journal-title":"Chin. J. Health Psychol."},{"key":"S0192415X24500861BIB020","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2009.03.003"},{"key":"S0192415X24500861BIB021","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2022.101747"},{"key":"S0192415X24500861BIB022","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20974"},{"key":"S0192415X24500861BIB023","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-023-02384-1"},{"key":"S0192415X24500861BIB024","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17010031"},{"key":"S0192415X24500861BIB025","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2022.923411"},{"key":"S0192415X24500861BIB026","first-page":"1129","volume":"38","author":"Li C.J.","year":"2019","journal-title":"Beijing J. Tradit. Chin. Med."},{"key":"S0192415X24500861BIB027","doi-asserted-by":"publisher","DOI":"10.5888\/pcd12.140413"},{"key":"S0192415X24500861BIB028","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25787"},{"key":"S0192415X24500861BIB029","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2022-330967"},{"key":"S0192415X24500861BIB030","doi-asserted-by":"publisher","DOI":"10.32604\/ijmhp.2022.021508"},{"key":"S0192415X24500861BIB031","first-page":"55","volume":"28","author":"Ling Y.","year":"2018","journal-title":"China Health Nutr."},{"key":"S0192415X24500861BIB032","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23823"},{"key":"S0192415X24500861BIB033","first-page":"3388","volume":"37","author":"Liu F.C.","year":"2023","journal-title":"Nurs. Res."},{"key":"S0192415X24500861BIB034","first-page":"34","volume":"24","author":"Liu X.L.","year":"2017","journal-title":"Chin. J. Neuroimmunol. Neurol."},{"key":"S0192415X24500861BIB035","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctcp.2020.101169"},{"key":"S0192415X24500861BIB036","first-page":"23","volume":"4","author":"Moon S.","year":"2017","journal-title":"Medicines (Basel)"},{"key":"S0192415X24500861BIB037","volume":"3","author":"Nocera J.R.","year":"2013","journal-title":"J. Yoga Phys. Ther."},{"key":"S0192415X24500861BIB038","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n160"},{"key":"S0192415X24500861BIB039","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2021.04.011"},{"key":"S0192415X24500861BIB040","first-page":"79","volume":"42","author":"Qu X.J.","year":"2023","journal-title":"Shandong J. Chin. Med."},{"key":"S0192415X24500861BIB041","doi-asserted-by":"publisher","DOI":"10.1007\/s40263-017-0450-z"},{"key":"S0192415X24500861BIB042","doi-asserted-by":"publisher","DOI":"10.1038\/nrn.2017.62"},{"key":"S0192415X24500861BIB043","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20705"},{"key":"S0192415X24500861BIB044","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27602"},{"key":"S0192415X24500861BIB045","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/8833736"},{"key":"S0192415X24500861BIB046","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctim.2023.102953"},{"key":"S0192415X24500861BIB047","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4898"},{"key":"S0192415X24500861BIB048","first-page":"836","volume":"26","author":"Sun W.Y.","year":"2020","journal-title":"Chin. J. Rehabil. Theor. Pract."},{"key":"S0192415X24500861BIB049","doi-asserted-by":"publisher","DOI":"10.1177\/1545968317753682"},{"key":"S0192415X24500861BIB050","doi-asserted-by":"publisher","DOI":"10.1038\/srep41581"},{"key":"S0192415X24500861BIB051","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(21)00061-2"},{"key":"S0192415X24500861BIB052","first-page":"3309","volume":"29","author":"Wang J.Z.","year":"2016","journal-title":"Med. Theor. Pract."},{"key":"S0192415X24500861BIB053","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2021.770920"},{"key":"S0192415X24500861BIB054","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.115.002562"},{"key":"S0192415X24500861BIB055","doi-asserted-by":"publisher","DOI":"10.1016\/j.gerinurse.2022.05.014"},{"key":"S0192415X24500861BIB056","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.961938"},{"key":"S0192415X24500861BIB057","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061038"},{"key":"S0192415X24500861BIB058","first-page":"27","volume":"26","author":"Wei N.","year":"2019","journal-title":"Modern Nurs."},{"key":"S0192415X24500861BIB059","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31824d587f"},{"key":"S0192415X24500861BIB061","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.927315"},{"key":"S0192415X24500861BIB062","first-page":"95","volume":"33","author":"Wu T.T.","year":"2018","journal-title":"Chin. J. Rehabil."},{"key":"S0192415X24500861BIB063","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.12571"},{"key":"S0192415X24500861BIB064","doi-asserted-by":"crossref","first-page":"e0122469","DOI":"10.1371\/journal.pone.0122469","volume":"10","author":"Yang Y.","year":"2015","journal-title":"PLoS One"},{"key":"S0192415X24500861BIB065","first-page":"6637612","volume":"2021","author":"Yu X.","year":"2021","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"S0192415X24500861BIB066","first-page":"1701","volume":"49","author":"Zhang Z.Z.","year":"2020","journal-title":"Shanxi Med. J."},{"key":"S0192415X24500861BIB067","doi-asserted-by":"publisher","DOI":"10.1111\/cns.13549"},{"key":"S0192415X24500861BIB068","doi-asserted-by":"publisher","DOI":"10.23736\/S0022-4707.19.10104-1"},{"key":"S0192415X24500861BIB069","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph15020321"}],"container-title":["The American Journal of Chinese Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.worldscientific.com\/doi\/pdf\/10.1142\/S0192415X24500861","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T05:28:47Z","timestamp":1736141327000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.worldscientific.com\/doi\/10.1142\/S0192415X24500861"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":68,"journal-issue":{"issue":"08","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1142\/S0192415X24500861"],"URL":"https:\/\/doi.org\/10.1142\/s0192415x24500861","relation":{},"ISSN":["0192-415X","1793-6853"],"issn-type":[{"value":"0192-415X","type":"print"},{"value":"1793-6853","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]}}}