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Med."],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Paeoniae Radix Alba (PRA, called Baishao in China) is the dried root of Paeonia lactiflora Pall. In clinical practice, PRA has been used to treat cardiovascular disease, menstrual disorders, abdominal pain, diarrhea, and liver disease, among other conditions. This review provides a systematic summary of its traditional uses, geographical distribution and current cultivation situation, phytochemistry, pharmacokinetics, pharmacology, quality control, and toxicology. Moreover, this review also serves as an in-depth discussion on the shortcomings of the current research on PRA, a subject not previously discussed in reviews regarding PRA, and puts forward its own views and solutions. So far, more needs to be done to understand the mechanism of action of PRA, as well as the relationships between its chemical components and their potential synergistic and antagonistic effects. 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