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Within the framework of Traditional Chinese Medicine (TCM), which has been extensively applied in the management of chronic conditions, specific herbal remedies, such as Paeonia lactiflora for rheumatoid arthritis, and Angelica sinensis and Codonopsis pilosula for cardiovascular regulation, have clinically relevant efficacy. In recent years, bioactive peptides (BAPs) derived from Chinese medicinal herbs, including peptides from Cordyceps sinensis and Panax ginseng, have drawn considerable international attention for their anti-inflammatory potential. This review delineates the principal methodologies for the extraction, isolation, and purification of anti-inflammatory peptides derived from medicinal herbs, highlights recent advances in their therapeutic application for inflammatory disorders, critically assesses existing barriers to clinical translation, and outlines future research priorities. <\/jats:p>","DOI":"10.1142\/s0192415x25500739","type":"journal-article","created":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T09:32:02Z","timestamp":1756978322000},"page":"1951-1982","source":"Crossref","is-referenced-by-count":5,"title":["Anti-Inflammatory Effects of Bioactive Peptides from Chinese Herbal Medicine: A Review"],"prefix":"10.1142","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4431-3347","authenticated-orcid":false,"given":"Rujia","family":"Cui","sequence":"first","affiliation":[{"name":"College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, 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