{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:09:35Z","timestamp":1759961375453},"reference-count":0,"publisher":"World Scientific Pub Co Pte Lt","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Chin. Med."],"published-print":{"date-parts":[[1993,1]]},"abstract":"<jats:p> The inhibitory effect of Orenge dokuto on lipid peroxide and sialidase was investigated using rats affected with carrageenin cotton pellet-induced granuloma and adjuvant arthritis. As a result, in the case of rats with carrageenin cotton pellet-induced granuloma, a significant inhibitory effect on granuloma formation was observed in the Orengedokuto treated rats (150 mg\/kg\/day) which showed a decrease in serum lipid peroxide ( p &lt;0.001) and an increase in acid soluble glycoprotein ( p &lt;0.001). In the case of adjuvant-induced arthritic rats, however, the condition of the arthritis was not improved at all, and was even aggravated in spite of the decrease in serum lipid peroxide. <\/jats:p>","DOI":"10.1142\/s0192415x93000091","type":"journal-article","created":{"date-parts":[[2004,11,30]],"date-time":"2004-11-30T03:17:30Z","timestamp":1101784650000},"page":"71-78","source":"Crossref","is-referenced-by-count":15,"title":["The Effect of Orengedokuto on Experimentally-inflamed Rats"],"prefix":"10.1142","volume":"21","author":[{"given":"Hiromi","family":"Mizukawa","sequence":"first","affiliation":[{"name":"The Kanagawa Rehabilitation Institute, 1304, Nanasawa, Atsugi-shi, Kanagawa, 243-01, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Yoshida","sequence":"additional","affiliation":[{"name":"The Kanagawa Rehabilitation Institute, 1304, Nanasawa, Atsugi-shi, Kanagawa, 243-01, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akie","family":"Honmura","sequence":"additional","affiliation":[{"name":"The Kanagawa Rehabilitation Institute, 1304, Nanasawa, Atsugi-shi, Kanagawa, 243-01, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiko","family":"Uchiyama","sequence":"additional","affiliation":[{"name":"The Kanagawa Rehabilitation Institute, 1304, Nanasawa, Atsugi-shi, Kanagawa, 243-01, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidehiko","family":"Kaku","sequence":"additional","affiliation":[{"name":"The Kanagawa Rehabilitation Institute, 1304, Nanasawa, Atsugi-shi, Kanagawa, 243-01, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigekatsu","family":"Nakajima","sequence":"additional","affiliation":[{"name":"The Kanagawa Rehabilitation Institute, 1304, Nanasawa, Atsugi-shi, Kanagawa, 243-01, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiichi","family":"Haruki","sequence":"additional","affiliation":[{"name":"The Kanagawa Rehabilitation Institute, 1304, Nanasawa, Atsugi-shi, Kanagawa, 243-01, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2012,4,5]]},"container-title":["The American Journal of Chinese Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.worldscientific.com\/doi\/pdf\/10.1142\/S0192415X93000091","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T00:17:40Z","timestamp":1565137060000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.worldscientific.com\/doi\/abs\/10.1142\/S0192415X93000091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,1]]},"references-count":0,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2012,4,5]]},"published-print":{"date-parts":[[1993,1]]}},"alternative-id":["10.1142\/S0192415X93000091"],"URL":"https:\/\/doi.org\/10.1142\/s0192415x93000091","relation":{},"ISSN":["0192-415X","1793-6853"],"issn-type":[{"value":"0192-415X","type":"print"},{"value":"1793-6853","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,1]]}}}