{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:59:14Z","timestamp":1760061554905},"reference-count":0,"publisher":"World Scientific Pub Co Pte Lt","issue":"02","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Chin. Med."],"published-print":{"date-parts":[[1997,1]]},"abstract":"<jats:p> This study was carried out to examine the effect of an aqueous extract from Siegesbeckia pubescens (Compositae) (SPAE) on immunoglobulin E (IgE)-mediated immediate hypersensitivity reaction. Forty-eight hours passive cutaneous anaphylaxis in rats was significantly inhibited by oral administration of SPAE (100 \u03bcg\/g). It also inhibited histamine release from rat peritoneal mast cells induced by anti-dinitrophenyl (DNP)-IgE and DNP-human serum albumin. The data indicate that SPAE has antiallergic activity, and that its action may be due to inhibition of histamine release from mast cells. <\/jats:p>","DOI":"10.1142\/s0192415x97000184","type":"journal-article","created":{"date-parts":[[2003,12,29]],"date-time":"2003-12-29T04:12:42Z","timestamp":1072671162000},"page":"163-167","source":"Crossref","is-referenced-by-count":14,"title":["Effects of <i>Siegesbeckia pubescens<\/i> on Immediate Hypersensitivity Reaction"],"prefix":"10.1142","volume":"25","author":[{"given":"Hyung Min","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Shinyong-Dong 344-2, Iksan, Chonbuk 570-749, South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2012,4,5]]},"container-title":["The American Journal of Chinese Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.worldscientific.com\/doi\/pdf\/10.1142\/S0192415X97000184","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T11:16:14Z","timestamp":1565176574000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.worldscientific.com\/doi\/abs\/10.1142\/S0192415X97000184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,1]]},"references-count":0,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2012,4,5]]},"published-print":{"date-parts":[[1997,1]]}},"alternative-id":["10.1142\/S0192415X97000184"],"URL":"https:\/\/doi.org\/10.1142\/s0192415x97000184","relation":{},"ISSN":["0192-415X","1793-6853"],"issn-type":[{"value":"0192-415X","type":"print"},{"value":"1793-6853","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,1]]}}}