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PHU prevented the increase in hepatic glutathione (GSH) and lipid peroxidation induced by CCl<jats:sub>4<\/jats:sub>. But PHU enhanced the increase in hepatic GSH caused by ANIT. These results indicate that the effect of PHU on hepatic GSH concentrations is through an indirect pathway. Clinical application of PHU on hepatitis should be explored further.<\/jats:p>","DOI":"10.1142\/s0192415x98000385","type":"journal-article","created":{"date-parts":[[2003,12,23]],"date-time":"2003-12-23T09:08:36Z","timestamp":1072170516000},"page":"343-351","source":"Crossref","is-referenced-by-count":7,"title":["Effect of Pretreatment of Rats with an Urinary Preparation on Liver Injuries Induced by Carbon Tetrachloride and \u03b1-Naphthylisothiocyanate"],"prefix":"10.1142","volume":"26","author":[{"given":"Tung-Yuan","family":"Lai","sequence":"first","affiliation":[{"name":"Graduate Institute of Chinese Pharmaceutical Sciences, China Medical College, 91 Hsueh Shih Road, Taichung, Taiwan, R.O.C"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yueh-Wern","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, China Medical College, 91 Hsueh Shih Road, Taichung, Taiwan, R.O.C"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaung-Geng","family":"Lin","sequence":"additional","affiliation":[{"name":"Research Institute of Chinese Medicine, China Medical College, 91 Hsueh Shih Road, Taichung, Taiwan, R.O.C"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Chuan","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, China Medical College, 91 Hsueh Shih Road, Taichung, Taiwan, R.O.C"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2012,4,5]]},"reference":[{"key":"p_2","first-page":"412","volume":"256","author":"Dahm L.J.","year":"1991","journal-title":"J. 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