{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T13:07:25Z","timestamp":1778591245402,"version":"3.51.4"},"reference-count":17,"publisher":"World Scientific Pub Co Pte Ltd","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am. J. Chin. Med."],"published-print":{"date-parts":[[1999,1]]},"abstract":"<jats:p>This study was carried out to examine the effect of methanol extract of Oryza sativa L. (Dong-Jin in Korean, abbreviate as Os-DJ hereafter) on anaphylaxis. Os-DJ (10<jats:sup>-5<\/jats:sup>to 1 g\/kg) dose-dependently inhibited systemic anaphylaxis induced by compound 48\/80 in rats. When Os-DJ was pretreated at concentration ranging from 10<jats:sup>-5<\/jats:sup>to 1 g\/kg, the serum histamine levels were reduced in a dose-dependent manner. Os-DJ (1 g\/kg) also significantly inhibited local anaphylaxis activated by anti-dinitrophenyl (DNP) IgE. Moreover, Os-DJ dose-dependently inhibited the histamine release from rat peritoneal mast cells (RPMC) activated by compound 48\/80 or anti-DNP IgE. These results indicate that Os-DJ possess anti anaphylactic activity by inhibition of histamine release from mast cells in vivo and in vitro.<\/jats:p>","DOI":"10.1142\/s0192415x99000094","type":"journal-article","created":{"date-parts":[[2003,11,10]],"date-time":"2003-11-10T03:20:35Z","timestamp":1068434435000},"page":"63-71","source":"Crossref","is-referenced-by-count":10,"title":["The Evaluation of Antianaphylactic Effect of<i>Oryza sativa<\/i>L. in Rats"],"prefix":"10.1142","volume":"27","author":[{"given":"Hyung Min","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan, Chonbuk, 570-749, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Kue","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan, Chonbuk, 570-749, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Young","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan, Chonbuk, 570-749, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"219","published-online":{"date-parts":[[2012,4,5]]},"reference":[{"key":"p_1","doi-asserted-by":"crossref","first-page":"22613","DOI":"10.1016\/S0021-9258(18)54615-9","volume":"266","author":"Alber G.","year":"1991","journal-title":"J. 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